Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210215 | 0.79 | BRD4 (0.53) | ALDH1A1HPGDLMNANOTUMKDM4E | |
| SCHEMBL9956357 | 0.79 | NOTUM (0.47) | NOTUMMEN1KMT2A | |
| SCHEMBL297366 | 0.77 | NOTUM (0.47) | ALDH1A1HPGDLMNANOTUMKDM4E | |
| SCHEMBL6723595 | 0.69 | PTGS2 (0.41) | — | |
| SCHEMBL15614395 | 0.68 | ERCC1 (0.65) | ALDH1A1HPGDLMNAKDM4EAHR | |
| SCHEMBL18603164 | 0.68 | NOTUM (0.50) | ALDH1A1NOTUM | |
| SCHEMBL8987318 | 0.68 | HPGD (0.55) | ALDH1A1HPGDLMNANOTUMKDM4E | |
| SCHEMBL17016676 | 0.68 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNAKDM4EAHR | |
| SCHEMBL10827519 | 0.68 | GABRP (0.51) | ALDH1A1HPGDLMNANOTUMGABRP | |
| SCHEMBL198702 | 0.67 | TAAR1 (0.68) | NOTUMKDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466833-A | Chiral 2-oxazolidinone and asymmetric synthesis method thereof | 三峡大学 | 2024-01-30 | — | — | CN | disclosed |
| WO-2012085852-A1 | 3,8-DIAZA-BICYCLO[4.2.0]OCT-8-YL AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012085857-A1 | 3,8-DIAZA-BICYCLO[4.2.0]OCT-3-YL AMIDES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-28 | — | — | WO | disclosed |