Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25075983 | 0.85 | MLYCD (0.36) | ALDH1A1TSHR | |
| SCHEMBL5618585 | 0.74 | — | — | |
| SCHEMBL1786636 | 0.74 | LPAR1 (0.32) | — | |
| SCHEMBL5013639 | 0.72 | NR1I2 (0.31) | — | |
| SCHEMBL9351985 | 0.72 | NOS2 (0.30) | — | |
| SCHEMBL8969981 | 0.72 | — | — | |
| SCHEMBL264582 | 0.67 | KDM4E (0.38) | ALDH1A1 | |
| SCHEMBL20672070 | 0.67 | MLYCD (0.34) | — | |
| SCHEMBL21235968 | 0.67 | — | — | |
| SCHEMBL967624 | 0.67 | MLYCD (0.37) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2650284-A1 | Heterocyclic derivatives as metabotropic glutamate receptor modulators | Merz Pharma GmbH & Co. KGaA (DE) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012085167-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-06-28 | — | — | WO | disclosed |