Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967314 | 0.85 | MLYCD (0.36) | NOS2 | |
| SCHEMBL21911886 | 0.77 | MGAM (0.35) | — | |
| SCHEMBL19182940 | 0.76 | NOS2 (0.39) | NOS2 | |
| SCHEMBL1786636 | 0.74 | LPAR1 (0.32) | — | |
| SCHEMBL5618585 | 0.74 | — | — | |
| SCHEMBL2580449 | 0.74 | NOS2 (0.32) | NOS2 | |
| SCHEMBL967485 | 0.74 | NOS2 (0.32) | NOS2 | |
| Hydrochloric Acid SCHEMBL15792343 | 0.74 | NOS2 (0.38) | NOS2 | |
| SCHEMBL5013639 | 0.72 | NR1I2 (0.31) | NOS2 | |
| SCHEMBL9955043 | 0.72 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610472-A1 | STEROIDS WITH A FLUORINATED ACYLUREIDIC TYPE SIDE CHAIN | PHARMACIA & UPJOHN S.p.A. (IT) | 1994-08-17 | — | — | EP | disclosed |
| WO-1994003474-A1 | STEROIDS WITH A FLUORINATED ACYLUREIDIC TYPE SIDE CHAIN | PHARMACIA/FARMITALIA CARLO ERBA SRL (IT) | 1994-02-17 | — | — | WO | disclosed |