SCHEMBL1786636

SCHEMBL1786636

O=C(O)N(CC(F)(F)F)CC(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LPAR1 Q92633 4/20 0.32
LPAR5 Q9H1C0 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL967624 0.85 MLYCD (0.37) LPAR1LPAR5
SCHEMBL1768632 0.83 FAAH (0.32)
SCHEMBL18274578 0.79 LPAR1 (0.35) LPAR1LPAR5
SCHEMBL1758795 0.78 CA12 (0.45)
SCHEMBL5618585 0.77
SCHEMBL20819811 0.76 LIMK1 (0.32)
SCHEMBL18274568 0.76 MLYCD (0.42) LPAR1LPAR5
SCHEMBL1758831 0.75 FAAH (0.46)
SCHEMBL15225307 0.75 FAAH (0.46)
SCHEMBL8969981 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067651-A1 PRODRUGS OF MYELOPEROXIDASE INHIBITORS BIOHAVEN THERAPEUTICS LTD. 2024-02-29 US disclosed
EP-2316822-B1 PREPARATION OF CARBAMATES WITH SOLID CATALYSTS CONSEJO SUPERIOR INVESTIGACION (ES) 2016-10-26 EP disclosed
US-8735621-B2 Preparation of carbamates with solid catalysts CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) 2014-05-27 US disclosed
US-20110124902-A1 PREPARATION OF CARBAMATES WITH SOLID CATALYSTS Consejo Superior De Investigaciones Cientificas C/Serrano, 117 (ES) 2011-05-26 US disclosed
EP-2316822-A1 PREPARATION OF CARBAMATES WITH SOLID CATALYSTS Consejo Superior De Investigaciones Científicas (ES) 2011-05-04 EP disclosed
US-7247757-B2 Method of producing a fluorine-containing vinyl ether compound FUJIFILM CORPORATION (JP) 2007-07-24 US disclosed
US-20060074264-A1 Method of producing a flourine-containing vinyl ether compound FUJI PHOTO FILM CO., LTD. 2006-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124902-A1 PREPARATION OF CARBAMATES WITH SOLID CATALYSTS ODC1, RCC1, OTC LPAR1 3311/4885LPAR5 2711/4885
US-20240067651-A1 PRODRUGS OF MYELOPEROXIDASE INHIBITORS MPO, CAT, SOD1 LPAR1 1597/4885LPAR5 1616/4885
US-20060074264-A1 Method of producing a flourine-containing vinyl ether compound AFF1, INF2, AFF2 LPAR1 2639/4885LPAR5 3293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.