Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954480 | 0.90 | L3MBTL1 (0.46) | LMNATP53MAPTTHRBCYP1A2 | |
| SCHEMBL9953429 | 0.90 | TP53 (0.45) | LMNATP53MAPTTHRBCYP1A2 | |
| SCHEMBL9955119 | 0.89 | MAPT (0.46) | LMNATP53MAPTTHRBCYP1A2 | |
| SCHEMBL9953908 | 0.88 | TP53 (0.47) | LMNATP53MAPTTHRBCYP1A2 | |
| SCHEMBL9954573 | 0.86 | USP1 (0.47) | LMNATP53MAPTTHRBCYP1A2 | |
| SCHEMBL9953491 | 0.85 | HCAR1 (0.41) | LMNATP53MAPTTHRBCYP1A2 | |
| SCHEMBL9954899 | 0.85 | SMN1; SMN2 (0.47) | LMNATP53MAPTTHRBCYP1A2 | |
| SCHEMBL9953750 | 0.84 | CYP3A4 (0.44) | LMNATP53MAPTTHRBCYP1A2 | |
| SCHEMBL9955121 | 0.83 | MAPT (0.46) | MAPTTHRBCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9953654 | 0.83 | TP53 (0.42) | LMNATP53MAPTTHRBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |