Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.47 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12661581 | 0.84 | PKM (0.50) | PKMTRPM4HPRT1PTPN22ALDH1A1 | |
| SCHEMBL10535788 | 0.81 | CASP6 (0.48) | PKMTRPM4HPRT1PTPN22ALDH1A1 | |
| SCHEMBL4927955 | 0.81 | TSHR (0.46) | PKMHPRT1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL7128617 | 0.79 | PTPN22 (0.45) | PKMTRPM4HPRT1PTPN22ALDH1A1 | |
| SCHEMBL50068 | 0.79 | TRPM4 (0.50) | PKMTRPM4PTPN22ALDH1A1HSD17B10 | |
| SCHEMBL9233004 | 0.79 | TRPM4 (0.61) | TRPM4PTPN22ALDH1A1HSD17B10HIF1A | |
| SCHEMBL30364741 | 0.79 | TRPM4 (0.50) | PKMTRPM4PTPN22ALDH1A1HSD17B10 | |
| SCHEMBL8655957 | 0.79 | ALDH1A1 (0.44) | PKMHPRT1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL29771816 | 0.79 | TRPM4 (0.61) | TRPM4PTPN22ALDH1A1HSD17B10HIF1A | |
| SCHEMBL20036860 | 0.79 | CYP1A2 (0.43) | PKMHPRT1ALDH1A1HSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456306-A1 | VITAMIN C AND VITAMIN K, AND COMPOSITIONS THEREOF FOR TREATMENT OF OSTEOLYSIS OR PROLONGATION OF PROSTHETIC IMPLANT | Summa Health System (US) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011011317-A1 | VITAMIN C AND VITAMIN K, AND COMPOSITIONS THEREOF FOR TREATMENT OF OSTEOLYSIS OR PROLONGATION OF PROSTHETIC IMPLANT | SUMMA HEALTH SYSTEM (US) | 2011-01-27 | — | — | WO | disclosed |