Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | CYP27A1 | Q02318 | 1/20 | 0.31 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10085736 | 0.87 | PDE4B (0.35) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL9955849 | 0.87 | ALOX5 (0.35) | PDE4BPDE4APDE4CPDE4DALOX5 | |
| SCHEMBL14645764 | 0.82 | ACHE (0.45) | PDE4BPDE4APDE4CPDE4DALOX5 | |
| SCHEMBL18772390 | 0.81 | HSP90AB1 (0.33) | PDE4D | |
| SCHEMBL9957468 | 0.81 | ERBB2 (0.32) | EGFRERBB2 | |
| SCHEMBL23940035 | 0.80 | GPR119 (0.32) | ACHE | |
| SCHEMBL14645606 | 0.77 | ACHE (0.34) | ACHE | |
| SCHEMBL21451184 | 0.75 | CNR2 (0.33) | — | |
| SCHEMBL31355494 | 0.75 | CNR2 (0.33) | — | |
| SCHEMBL20180227 | 0.74 | CNR2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2995629-B1 | Process for producing propylene copolymers in gas phase | BOREALIS AG (AT) | 2018-03-07 | — | — | EP | disclosed |
| US-20170247484-A1 | PROCESS FOR PRODUCING PROPYLENE COPOLYMERS IN GAS PHASE | BOREALIS AG (AT) | 2017-08-31 | — | — | US | disclosed |
| EP-2995629-A1 | Process for producing propylene copolymers in gas phase | Borealis AG (AT) | 2016-03-16 | — | — | EP | disclosed |
| EP-2657285-B1 | moulded polypropylene with high content of beta form | BOREALIS AG (AT) | 2015-07-22 | — | — | EP | disclosed |
| US-9079985-B2 | Bridged metallocene catalysts | BOREALIS AG (AT) | 2015-07-14 | — | — | US | disclosed |
| US-9079985-B2 | Bridged metallocene catalysts | BOREALIS AG (AT) | 2015-07-14 | — | — | US | disclosed |
| US-20140018506-A1 | BRIDGED METALLOCENE CATALYSTS | BOREALIS AG (AT) | 2014-01-16 | — | — | US | disclosed |
| US-20140018506-A1 | BRIDGED METALLOCENE CATALYSTS | BOREALIS AG (AT) | 2014-01-16 | — | — | US | disclosed |
| EP-2655431-A1 | BRIDGED METALLOCENE CATALYSTS | Borealis AG (AT) | 2013-10-30 | — | — | EP | disclosed |
| EP-2657285-A1 | Moulded polypropylene with high content of beta form | Borealis AG (AT) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012084961-A1 | BRIDGED METALLOCENE CATALYSTS | BOREALIS AG (AT) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012084961-A1 | BRIDGED METALLOCENE CATALYSTS | BOREALIS AG (AT) | 2012-06-28 | — | — | WO | disclosed |