SCHEMBL20180227

SCHEMBL20180227

COc1c(C(C)(C)C)cc2c(c1-c1cc(C)cc(C)c1)CC(CC(C)(C)C)C2=O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20165751 1.00 CNR2 (0.31) CNR2
SCHEMBL29874522 1.00 CNR2 (0.31) CNR2
SCHEMBL20180234 0.90 CNR2 (0.31) CNR2
SCHEMBL21451184 0.90 CNR2 (0.33) CNR2
SCHEMBL31355494 0.90 CNR2 (0.33) CNR2
SCHEMBL9955849 0.87 ALOX5 (0.35)
SCHEMBL22863196 0.84 ACHE (0.42) CNR2
SCHEMBL20180147 0.84 ACHE (0.42) CNR2
SCHEMBL20165703 0.84 ACHE (0.42) CNR2
SCHEMBL31342804 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110177798-B Catalyst and process for preparing same 博里利斯股份公司 2022-08-30 CN disclosed
US-11352376-B2 Catalysts BOREALIS AG (AT) 2022-06-07 US disclosed
US-11352376-B2 Catalysts BOREALIS AG (AT) 2022-06-07 US disclosed
EP-3541823-B1 CATALYSTS BOREALIS AG (AT) 2020-12-30 EP disclosed
EP-3541823-B1 CATALYSTS BOREALIS AG (AT) 2020-12-30 EP disclosed
US-20190308995-A1 CATALYSTS BOREALIS AG (AT) 2019-10-10 US disclosed
US-20190308995-A1 CATALYSTS BOREALIS AG (AT) 2019-10-10 US disclosed
WO-2018091684-A1 CATALYSTS BOREALIS AG (AT) 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352376-B2 Catalysts SIGMAR1, H1-2, SFN CNR2 480/4885
US-20190308995-A1 CATALYSTS SIGMAR1, H1-2, CBR1 CNR2 356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.