Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | FABP1 | P07148 | 2/20 | 0.46 |
| ▸ | F2 | P00734 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12474952 | 0.97 | ALPL (0.51) | ALPLFABP1F2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9955131 | 0.87 | FABP1 (0.44) | ALPLFABP1F2ALDH1A1SMN1; SMN2 | |
| SCHEMBL12474801 | 0.84 | ALDH1A1 (0.45) | ALPLFABP1F2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10289065 | 0.77 | ITK (0.48) | FABP1F2MAPT | |
| SCHEMBL10288674 | 0.76 | ALPL (0.70) | ALPLNPC1MEN1KMT2AMAPT | |
| SCHEMBL9955125 | 0.75 | F2 (0.51) | FABP1F2ALDH1A1SMN1; SMN2DRD2 | |
| SCHEMBL4544125 | 0.72 | KDM4E (0.62) | ALDH1A1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL16926583 | 0.71 | CDK1 (0.60) | ALPLMEN1KMT2AMAPT | |
| SCHEMBL790242 | 0.70 | ALPL (0.58) | ALPLFABP1F2ALDH1A1SMN1; SMN2 | |
| SCHEMBL17163970 | 0.70 | DRD2 (0.64) | ALDH1A1KMT2ADRD2DRD4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |