Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP1 | P07148 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | ALPL | P05186 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12474801 | 0.97 | ALDH1A1 (0.45) | FABP1F2ALPLALDH1A1SMN1; SMN2 | |
| SCHEMBL10289065 | 0.89 | ITK (0.48) | FABP1F2SHMT2PIK3C3MAPT | |
| SCHEMBL9955800 | 0.87 | ALPL (0.50) | FABP1F2ALPLALDH1A1SMN1; SMN2 | |
| SCHEMBL12474952 | 0.84 | ALPL (0.51) | FABP1F2ALPLALDH1A1SMN1; SMN2 | |
| SCHEMBL790242 | 0.83 | ALPL (0.58) | FABP1F2ALPLALDH1A1SMN1; SMN2 | |
| SCHEMBL806765 | 0.83 | LMNA (0.53) | ALPLALDH1A1SMN1; SMN2SHMT2LMNA | |
| SCHEMBL789685 | 0.80 | ALPL (0.59) | FABP1F2ALPLALDH1A1SMN1; SMN2 | |
| SCHEMBL9954777 | 0.78 | PIK3CD (0.56) | ALPLSHMT2MAPT | |
| SCHEMBL9954165 | 0.76 | PI4KA (0.65) | — | |
| SCHEMBL806782 | 0.76 | SMN1; SMN2 (0.54) | ALPLALDH1A1SMN1; SMN2SHMT2PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |