Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15674404 | 1.00 | ALOX5 (0.36) | ALOX5CYP3A4CYP2C9HSD11B1SMN1; SMN2 | |
| SCHEMBL956652 | 0.89 | SMN1; SMN2 (0.34) | ALOX5CYP3A4CYP2C9HSD11B1SMN1; SMN2 | |
| SCHEMBL10066610 | 0.87 | BCHE (0.33) | ALOX5CYP3A4CYP2C9HSD11B1SMN1; SMN2 | |
| SCHEMBL1431288 | 0.86 | ALOX5 (0.36) | ALOX5SMN1; SMN2KMT2AMEN1PMP22 | |
| SCHEMBL1431291 | 0.86 | ALOX5 (0.36) | ALOX5SMN1; SMN2KMT2AMEN1PMP22 | |
| SCHEMBL1431286 | 0.86 | ALOX5 (0.36) | ALOX5SMN1; SMN2KMT2AMEN1PMP22 | |
| SCHEMBL15675005 | 0.79 | HSD11B1 (0.45) | CYP3A4CYP2C9HSD11B1 | |
| SCHEMBL3670614 | 0.78 | CYP2C19 (0.37) | ALOX5SMN1; SMN2KMT2APMP22ALDH1A1 | |
| SCHEMBL958625 | 0.78 | UTS2R (0.38) | — | |
| SCHEMBL15163671 | 0.78 | UTS2R (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916701-B2 | Methods of making diastereomeric organic compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-23 | — | — | US | disclosed |
| EP-2655349-B1 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2014-10-15 | — | — | EP | disclosed |
| US-20140135493-A1 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-15 | — | — | US | disclosed |
| EP-2655349-A1 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087720-A1 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135493-A1 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS | HSD11B1, HSD11B2, HSD17B1 | ALOX5 347/4885CYP3A4 57/4885CYP2C9 72/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.