Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 19/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10066209 | 0.90 | HSD11B1 (0.42) | HSD11B1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL13624909 | 0.81 | HSD11B1 (0.44) | HSD11B1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL17120312 | 0.81 | HSD11B1 (0.44) | HSD11B1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL9955344 | 0.81 | HSD11B1 (0.42) | HSD11B1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL9955946 | 0.79 | ALOX5 (0.36) | HSD11B1CYP2C9CYP3A4 | |
| SCHEMBL15674404 | 0.79 | ALOX5 (0.36) | HSD11B1CYP2C9CYP3A4 | |
| SCHEMBL16374786 | 0.78 | KMT2A (0.35) | HSD11B1CYP2C9CYP2C19 | |
| SCHEMBL15241456 | 0.76 | HSD11B1 (0.47) | HSD11B1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL15241496 | 0.76 | HSD11B1 (0.45) | HSD11B1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL15436370 | 0.75 | HSD11B1 (0.46) | HSD11B1CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916701-B2 | Methods of making diastereomeric organic compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-12-23 | — | — | US | disclosed |
| EP-2655349-B1 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2014-10-15 | — | — | EP | disclosed |
| US-20140135493-A1 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140135493-A1 | METHODS OF MAKING DIASTEREOMERIC ORGANIC COMPOUNDS | HSD11B1, HSD11B2, HSD17B1 | HSD11B1 1/4885CYP2C9 72/4885CYP2C19 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.