Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 2/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CCR9 | P51686 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PPARD | Q03181 | 1/20 | 0.30 |
| ▸ | PPARA | Q07869 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578417 | 0.78 | MCL1 (0.38) | MAPTMEN1KMT2A | |
| SCHEMBL3574035 | 0.77 | MEP1B (0.36) | MEP1BCACNA1HPPARGPPARDPPARA | |
| SCHEMBL3579938 | 0.73 | MAPT (0.42) | MAPTMEN1KMT2AL3MBTL1TP53 | |
| SCHEMBL3578978 | 0.73 | CNR1 (0.43) | MEN1KMT2A | |
| SCHEMBL3577419 | 0.71 | NR1H4 (0.37) | MAPTMEN1KMT2ATP53 | |
| SCHEMBL3582291 | 0.69 | MCL1 (0.39) | MEN1KMT2A | |
| SCHEMBL3577275 | 0.69 | MCL1 (0.39) | MEN1KMT2A | |
| SCHEMBL3581034 | 0.69 | LPAR1 (0.36) | MEP1BCACNA1HPPARGPPARDPPARA | |
| SCHEMBL3571223 | 0.68 | MAPK14 (0.39) | MEN1KMT2ATSHR | |
| SCHEMBL3581360 | 0.67 | MCL1 (0.40) | PPARGPPARDPPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |