Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 3/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARD | Q03181 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3574035 | 0.92 | MEP1B (0.36) | LPAR1LPAR5MEP1BPPARGPPARD | |
| SCHEMBL3582291 | 0.87 | MCL1 (0.39) | SLC2A1LMNA | |
| SCHEMBL3574865 | 0.87 | LPAR1 (0.38) | LPAR1LPAR5MEP1BPPARGPPARD | |
| SCHEMBL3581545 | 0.84 | CNR1 (0.40) | LPAR1LPAR5PPARGPPARDPPARA | |
| SCHEMBL3571214 | 0.81 | CNR1 (0.38) | LPAR1LPAR5 | |
| SCHEMBL3576028 | 0.80 | MCL1 (0.39) | MAPK14SLC2A1LMNA | |
| SCHEMBL3569982 | 0.80 | LPAR1 (0.41) | LPAR1LPAR5MEP1BPPARGALDH1A1 | |
| SCHEMBL3577275 | 0.80 | MCL1 (0.39) | SLC2A1LMNA | |
| SCHEMBL3578417 | 0.79 | MCL1 (0.38) | ALDH1A1MAPTLMNA | |
| SCHEMBL3574236 | 0.78 | LMNA (0.40) | NPSR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |