Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ESRRG | P62508 | 5/20 | 0.40 |
| ▸ | ESRRB | O95718 | 2/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3579938 | 0.92 | MAPT (0.42) | CNR1MEN1KMT2AESRRGESRRB | |
| SCHEMBL3583039 | 0.91 | CNR1 (0.43) | CNR1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL3577052 | 0.89 | C5AR1 (0.37) | CNR1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL3589192 | 0.87 | PPARA (0.39) | C5AR1RCE1POLBSMN1; SMN2LPAR1 | |
| SCHEMBL3577419 | 0.85 | NR1H4 (0.37) | CYP1A2CYP2C19MEN1KMT2AESRRG | |
| SCHEMBL3581360 | 0.85 | MCL1 (0.40) | CNR1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL3584396 | 0.83 | C5AR1 (0.44) | CNR1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL3583296 | 0.83 | LPAR1 (0.52) | C5AR1RCE1EPHX2LPAR1LPAR5 | |
| SCHEMBL3581545 | 0.82 | CNR1 (0.40) | CNR1NR1H4EPHX2LPAR1LPAR5 | |
| SCHEMBL3580876 | 0.82 | LPAR1 (0.36) | CNR1C5AR1RCE1EPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |