SCHEMBL9956780

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27755760	0.79	MAOA (0.47)	ALDH1A1MAPTLMNAMEN1KMT2A
	SCHEMBL28328327	0.77	MAOA (0.42)	ALDH1A1MAPTLMNAL3MBTL1HNF4A
	SCHEMBL3552317	0.76	ALDH1A1 (0.51)	ALDH1A1MAPTLMNAL3MBTL1HNF4A
	SCHEMBL3552315	0.76	ALDH1A1 (0.51)	ALDH1A1MAPTLMNAL3MBTL1HNF4A
	SCHEMBL3552319	0.76	ALDH1A1 (0.51)	ALDH1A1MAPTLMNAL3MBTL1HNF4A
	SCHEMBL31670439	0.76	ALDH1A1 (0.51)	ALDH1A1MAPTLMNAL3MBTL1HNF4A
	SCHEMBL27736817	0.76	—	—
	SCHEMBL27715968	0.76	CA1 (0.36)	ALDH1A1MAPTLMNAL3MBTL1GAA
	SCHEMBL224931	0.75	GPR3 (0.41)	ALDH1A1LMNAMEN1KMT2APOLB
	SCHEMBL27818816	0.73	GPR3 (0.39)	ALDH1A1MEN1KMT2APOLBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.