Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL29349552 | 0.81 | ALDH1A1 (1.00) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| Quinoline SCHEMBL2774 | 0.81 | ALDH1A1 (1.00) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| Quinoline SCHEMBL1270969 | 0.81 | ALDH1A1 (1.00) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| Quinoline SCHEMBL32661377 | 0.81 | ALDH1A1 (1.00) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| Quinoline SCHEMBL29822171 | 0.81 | ALDH1A1 (1.00) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| Quinoline SCHEMBL5230994 | 0.79 | ALDH1A1 (0.85) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| Quinoline SCHEMBL23202414 | 0.79 | ALDH1A1 (0.94) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL3189055 | 0.79 | ALDH1A1 (0.94) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| Quinoline SCHEMBL1935828 | 0.79 | ALDH1A1 (0.94) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| Quinoline SCHEMBL5422407 | 0.79 | ALDH1A1 (0.94) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2668195-A1 | AROMATIC COMPOUNDS BEARING AT LEAST ONE PHOSPHONATE OR PHOSPHINATE GROUP, PREPARATION METHOD AND USES THEREOF | Rhodia (China) Co., Ltd. (CN) | 2013-12-04 | — | — | EP | claimed |
| US-20130274484-A1 | AROMATIC COMPOUNDS BEARING AT LEAST ONE PHOSPHONATE OR PHOSPHINATE GROUP, PREPARATION METHOD AND USES THEREOF | SOLVAY (CHINA) CO., LTD (CN) | 2013-10-17 | — | — | US | claimed |
| WO-2012083559-A1 | AROMATIC COMPOUNDS BEARING AT LEAST ONE PHOSPHONATE OR PHOSPHINATE GROUP, PREPARATION METHOD AND USES THEREOF | RHODIA (CHINA) CO., LTD. (CN) | 2012-06-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274484-A1 | AROMATIC COMPOUNDS BEARING AT LEAST ONE PHOSPHONATE OR PHOSPHINATE GROUP, PREPARATION METHOD AND USES THEREOF | PHOSPHO1, ATIC, ACP1 | ALDH1A1 1974/4885ABCG2 553/4885NPC1 4092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.