Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399691 | 0.70 | PDK1 (0.40) | ALDH1A1L3MBTL1PDK1MAPK1POLB | |
| SCHEMBL6247128 | 0.69 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1PDK1MAPK1POLB | |
| SCHEMBL3647529 | 0.67 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1PDK1MAPK1POLB | |
| SCHEMBL294985 | 0.67 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1PDK1MAPK1POLB | |
| SCHEMBL11826634 | 0.67 | PDK1 (0.41) | ALDH1A1L3MBTL1PDK1MAPK1POLB | |
| SCHEMBL8420199 | 0.65 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1PDK1MAPK1KDM4E | |
| SCHEMBL8420200 | 0.65 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1PDK1MAPK1KDM4E | |
| SCHEMBL8421030 | 0.65 | MAPK1 (0.47) | ALDH1A1L3MBTL1PDK1MAPK1POLB | |
| SCHEMBL8421032 | 0.65 | MAPK1 (0.47) | ALDH1A1L3MBTL1PDK1MAPK1POLB | |
| SCHEMBL8421034 | 0.65 | MAPK1 (0.47) | ALDH1A1L3MBTL1PDK1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468741-A1 | Novel quercetin derivatives, their preparation, pharmaceutical compositions containing them and their use | Bel/Novamann International s.r.o. (SK) | 2012-06-27 | — | — | EP | disclosed |