Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EBP | Q15125 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420199 | 1.00 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1PDK1MEN1KMT2A | |
| SCHEMBL6247128 | 0.79 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1PDK1MEN1KMT2A | |
| SCHEMBL11826634 | 0.77 | PDK1 (0.41) | ALDH1A1L3MBTL1PDK1MEN1KMT2A | |
| SCHEMBL38657611 | 0.72 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1PDK1MEN1KMT2A | |
| SCHEMBL3647529 | 0.72 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1PDK1MEN1KMT2A | |
| SCHEMBL294985 | 0.72 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1PDK1MEN1KMT2A | |
| SCHEMBL17010328 | 0.72 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1PDK1MEN1KMT2A | |
| SCHEMBL1214529 | 0.68 | L3MBTL1 (0.58) | ALDH1A1L3MBTL1MEN1KMT2APKM | |
| SCHEMBL11481807 | 0.66 | SIGMAR1 (0.46) | ALDH1A1L3MBTL1PDK1KMT2AEBP | |
| SCHEMBL9958144 | 0.65 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1PDK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585682-B1 | Process for the preparation of 2,6-dimethylmorpholine from N-(2-hydroxypropyl)-2,6-dimethylmorpholine | BASF AG (DE) | 1999-10-06 | — | — | EP | disclosed |
| US-5436335-A | Catalytic dealkylation using group Ib, IIb and group VIII metals | BASF AKTIENGESELLSCHAFT (DE) | 1995-07-25 | — | — | US | disclosed |
| EP-0585682-A2 | Process for the preparation of 2,6-dimethylmorpholine from N-(2-hydroxypropyl)-2,6-dimethylmorpholine | BASF Aktiengesellschaft (DE) | 1994-03-09 | — | — | EP | disclosed |