Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420199 | 0.79 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1PDK1EBPSIGMAR1 | |
| SCHEMBL8420200 | 0.79 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1PDK1EBPSIGMAR1 | |
| SCHEMBL3647529 | 0.76 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1PDK1EBPSIGMAR1 | |
| SCHEMBL11826634 | 0.76 | PDK1 (0.41) | ALDH1A1L3MBTL1PDK1EBPSIGMAR1 | |
| SCHEMBL294985 | 0.76 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1PDK1EBPSIGMAR1 | |
| SCHEMBL38657611 | 0.76 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1PDK1EBPSIGMAR1 | |
| SCHEMBL1374772 | 0.70 | — | — | |
| SCHEMBL11481807 | 0.69 | SIGMAR1 (0.46) | ALDH1A1L3MBTL1PDK1EBPSIGMAR1 | |
| SCHEMBL9958144 | 0.69 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1PDK1EBPSIGMAR1 | |
| SCHEMBL24051636 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668302-B1 | Catalyst for reactive hot melt adhesives | NAT STARCH CHEM INVEST (US) | 1999-12-22 | — | — | EP | claimed |
| WO-2019174279-A1 | 1,2-BENZISOSELENAZOL-3(2H)-ONE AND 1,2-BENZISOTHIAZOL-3(2H)-ONE DERIVATIVES AS BETA-LACTAM ANTIBIOTIC ADJUVANTS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2019-09-19 | — | — | WO | disclosed |
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |