Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9958528 | 0.93 | F2 (0.39) | F2F10F7C5AR1MCHR1 | |
| SCHEMBL3582819 | 0.81 | LMNA (0.38) | F2F10F7C5AR1MCHR1 | |
| SCHEMBL3579477 | 0.78 | MCHR1 (0.37) | F2F10F7C5AR1MCHR1 | |
| SCHEMBL3570656 | 0.75 | TP53 (0.42) | F2F10F7C5AR1MCHR1 | |
| SCHEMBL3577159 | 0.74 | C5AR1 (0.42) | F10C5AR1CA12CA1CA2 | |
| SCHEMBL12521064 | 0.74 | C5AR1 (0.45) | C5AR1MCHR1CA12CA1CA2 | |
| SCHEMBL3584582 | 0.74 | LMNA (0.38) | F2F10F7C5AR1MCHR1 | |
| SCHEMBL3583620 | 0.74 | MCHR1 (0.40) | F2F10F7C5AR1MCHR1 | |
| SCHEMBL3582155 | 0.73 | F2 (0.42) | F2F10F7C5AR1MCHR1 | |
| SCHEMBL3587697 | 0.73 | C5AR1 (0.41) | F10C5AR1NLRP3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |