Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 4/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.77 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.77 |
| ▸ | EIF4H | Q15056 | 3/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | CLK1 | P49759 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19617464 | 0.88 | HDAC6 (1.00) | HDAC6MEN1KMT2APABPC1EIF4H | |
| SCHEMBL19616383 | 0.85 | HDAC6 (0.74) | HDAC6MEN1KMT2APABPC1EIF4H | |
| SCHEMBL13762083 | 0.85 | MEN1 (1.00) | HDAC6MEN1KMT2APABPC1EIF4H | |
| SCHEMBL8620986 | 0.84 | MEN1 (0.73) | HDAC6MEN1KMT2APABPC1EIF4H | |
| SCHEMBL19976894 | 0.83 | ALDH1A1 (0.62) | HDAC6MEN1KMT2APABPC1EIF4H | |
| SCHEMBL27489211 | 0.83 | MEN1 (0.71) | HDAC6MEN1KMT2APABPC1EIF4H | |
| SCHEMBL13144407 | 0.83 | ADORA3 (0.64) | HDAC6MEN1KMT2APABPC1EIF4H | |
| SCHEMBL27599336 | 0.82 | MEN1 (0.76) | HDAC6MEN1KMT2APABPC1EIF4H | |
| SCHEMBL3148472 | 0.82 | NPC1 (0.82) | MEN1KMT2ACYP1A2CYP3A4KDR | |
| SCHEMBL12078784 | 0.80 | SMN1; SMN2 (0.61) | HDAC6MEN1KMT2APABPC1EIF4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3324954-B1 | AMINONAPTHOQUINONE COMPOUNDS AND PHARMACEUTICAL COMPOSITION FOR BLOCKING UBIQUITINATION-PROTEASOME SYSTEM IN DISEASES | CALGENT BIOTECHNOLOGY CO LTD (TW) | 2022-03-09 | — | — | EP | claimed |
| WO-2012100223-A1 | SYNTHETIC LETHAL TARGETING OF GLUCOSE TRANSPORT | IRWIN JOHN (US) | 2012-07-26 | — | — | WO | claimed |
| WO-2011011514-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-01-27 | — | — | WO | claimed |
| EP-4581017-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | Biodol Therapeutics (FR) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024079072-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | BIODOL THERAPEUTICS (FR) | 2024-04-18 | — | — | WO | disclosed |
| WO-2012100223-A1 | SYNTHETIC LETHAL TARGETING OF GLUCOSE TRANSPORT | IRWIN JOHN (US) | 2012-07-26 | — | — | WO | disclosed |
| WO-2011011514-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-01-27 | — | — | WO | disclosed |