SCHEMBL9958833

SCHEMBL9958833

CC(=O)Nc1ccc2c(c1)C(=O)N(O)C(=O)C2C(=O)NCc1ccc(F)cc1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
PRMT5 O14744 4/20 0.40
WDR77 Q9BQA1 4/20 0.40
RAB9A P51151 1/20 0.39
MEN1 O00255 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
PTPN1 P18031 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30675135 0.87 PRMT5 (0.47) ALDH1A1POLBSMN1; SMN2PRMT5WDR77
SCHEMBL9959338 0.87 KCNK3 (0.46) ALDH1A1POLBSMN1; SMN2RAB9AMEN1
SCHEMBL9952468 0.86 ALDH1A1 (0.50) ALDH1A1POLBSMN1; SMN2RAB9AMEN1
SCHEMBL9958767 0.85 CNR1 (0.45) ALDH1A1POLBPRMT5WDR77RAB9A
SCHEMBL29411937 0.85 CNR1 (0.45) ALDH1A1POLBPRMT5WDR77RAB9A
SCHEMBL9959336 0.85 RAB9A (0.42) ALDH1A1POLBSMN1; SMN2PRMT5WDR77
SCHEMBL30089105 0.84 KDR (0.47) ALDH1A1PRMT5WDR77
SCHEMBL9952596 0.84 KDR (0.47) ALDH1A1PRMT5WDR77
SCHEMBL9959238 0.83 ALDH1A1 (0.41) ALDH1A1POLBSMN1; SMN2PRMT5WDR77
SCHEMBL9959490 0.83 PRMT5 (0.42) ALDH1A1POLBSMN1; SMN2PRMT5WDR77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113630927-B Single-live-wire off-state micro-current mode selectable double-control capacitive touch switch 周福生 2024-03-19 CN claimed
EP-3843953-B1 METHOD FOR AUTOMATIC LOAD COMPENSATION FOR A COBOT OR AN UPPER LIMB EXOSKELETON COMMISSARIAT ENERGIE ATOMIQUE (FR) 2022-10-05 EP claimed
WO-2012085003-A1 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONES AND RELATED COMPOUNDS USEFUL AS HIV REPLICATION INHIBITORS KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) 2012-06-28 WO claimed
US-20260026340-A1 STACKED SEMICONDUCTOR DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-01-22 US disclosed
US-20240361131-A1 INFORMATION PROCESSING DEVICE, INFORMATION PROCESSING METHOD, AND STORAGE MEDIUM CANON KABUSHIKI KAISHA (JP) 2024-10-31 US disclosed
US-20240160237-A1 OVERCURRENT PROTECTION CIRCUIT AND SEMICONDUCTOR DEVICE ROHM CO., LTD. (JP) 2024-05-16 US disclosed
CN-117768082-A Memristor-based chaotic PUF circuit and use method thereof 武汉科技大学 2024-03-26 CN disclosed
CN-113630927-B Single-live-wire off-state micro-current mode selectable double-control capacitive touch switch 周福生 2024-03-19 CN disclosed
CN-117561486-A Overcurrent protection circuit and semiconductor device 罗姆股份有限公司 2024-02-13 CN disclosed
US-11776438-B2 Detecting method of pixel circuit, driving method of display panel and display device BOE TECHNOLOGY GROUP CO., LTD. (CN) 2023-10-03 US disclosed
CN-116656846-A Application of oral microorganisms as microorganism markers in preparation of kit for distinguishing diabetics 河南省人民医院 2023-08-29 CN disclosed
WO-2023149288-A1 INFORMATION PROCESSING DEVICE, INFORMATION PROCESSING METHOD, AND STORAGE MEDIUM キヤノン株式会社 2023-08-10 WO disclosed
CN-116536438-A Application of intestinal microorganisms as microorganism markers in preparation of kit for distinguishing pre-diabetic patients 河南省人民医院 2023-08-04 CN disclosed
US-20230208360-A1 OPERATIONAL AMPLIFIER ROHM CO., LTD. (JP) 2023-06-29 US disclosed
US-20230206792-A1 DETECTING METHOD OF PIXEL CIRCUIT, DRIVING METHOD OF DISPLAY PANEL AND DISPLAY DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2023-06-29 US disclosed
CN-115820858-B Application of serum in preparation of Yunnan Xuanwei lung cancer diagnosis medicine 昆明医科大学第一附属医院 2023-06-20 CN disclosed
CN-116194099-A Treatment of dilated cardiomyopathy 吉尼松公司 2023-05-30 CN disclosed
WO-2023276491-A1 OVERCURRENT PROTECTION CIRCUIT AND SEMICONDUCTOR DEVICE ローム株式会社 2023-01-05 WO disclosed
CN-110064046-B Application of mini-peptide YY1BM in treating cancer 苏州大学 2022-11-22 CN disclosed
WO-2012085003-A1 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONES AND RELATED COMPOUNDS USEFUL AS HIV REPLICATION INHIBITORS KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) 2012-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260026340-A1 STACKED SEMICONDUCTOR DEVICE KCNQ4, KCNQ5, VDAC1 ALDH1A1 3376/4885POLB 4434/4885SMN1; SMN2 2737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.