SCHEMBL9959338

SCHEMBL9959338

O=C(Nc1ccc2c(c1)C(=O)N(O)C(=O)C2C(=O)NCc1ccc(F)cc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 1/20 0.46
KCNK9 Q9NPC2 1/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
POLB P06746 2/20 0.43
CTDSP1 Q9GZU7 1/20 0.43
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.42
ALOX12 P18054 1/20 0.42
RECQL P46063 1/20 0.42
ACKR3 P25106 2/20 0.42
NAMPT P43490 1/20 0.42
HPGD P15428 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SNCA P37840 1/20 0.41
PPARG P37231 1/20 0.41
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9952468 0.88 ALDH1A1 (0.50) RAB9APOLBMEN1KMT2AALDH1A1
SCHEMBL9959336 0.88 RAB9A (0.42) NPC1RAB9APOLBMEN1KMT2A
SCHEMBL9952596 0.88 KDR (0.47) ALDH1A1
SCHEMBL30089105 0.88 KDR (0.47) ALDH1A1
SCHEMBL9958833 0.87 ALDH1A1 (0.42) RAB9APOLBMEN1KMT2AALDH1A1
SCHEMBL30675135 0.84 PRMT5 (0.47) POLBMEN1KMT2AALDH1A1LMNA
SCHEMBL9958767 0.82 CNR1 (0.45) RAB9APOLBALDH1A1
SCHEMBL29411937 0.82 CNR1 (0.45) RAB9APOLBALDH1A1
SCHEMBL9953409 0.82 POLB (0.50) RAB9APOLBALDH1A1SMN1; SMN2
SCHEMBL9952739 0.81 HPGD (0.54) NPC1RAB9APOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113595627-B Optical power calibration method based on space linear superposition principle 中国电子技术标准化研究院 2022-05-17 CN claimed
US-20260026340-A1 STACKED SEMICONDUCTOR DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-01-22 US disclosed
EP-3318870-B1 ADJUSTABLE FIXTURE FOR SCANNING ACOUSTIC MICROSCOPY SONIX INC (US) 2025-02-26 EP disclosed
US-20240361131-A1 INFORMATION PROCESSING DEVICE, INFORMATION PROCESSING METHOD, AND STORAGE MEDIUM CANON KABUSHIKI KAISHA (JP) 2024-10-31 US disclosed
CN-117756989-A Fluorine-containing zwitterionic ion with hyperbranched structure based on cyclodextrin nuclear point 19 FMRI contrast media and preparation thereof 中山大学 2024-03-26 CN disclosed
CN-117180447-A Use of IMMU-132 in preparing medicament for treating colorectal cancer 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) 2023-12-08 CN disclosed
CN-117083054-A Device for treating allergic reactions 1232176 B.C.有限公司 2023-11-17 CN disclosed
US-11776438-B2 Detecting method of pixel circuit, driving method of display panel and display device BOE TECHNOLOGY GROUP CO., LTD. (CN) 2023-10-03 US disclosed
CN-116656846-A Application of oral microorganisms as microorganism markers in preparation of kit for distinguishing diabetics 河南省人民医院 2023-08-29 CN disclosed
WO-2023149288-A1 INFORMATION PROCESSING DEVICE, INFORMATION PROCESSING METHOD, AND STORAGE MEDIUM キヤノン株式会社 2023-08-10 WO disclosed
US-20230208360-A1 OPERATIONAL AMPLIFIER ROHM CO., LTD. (JP) 2023-06-29 US disclosed
US-20230206792-A1 DETECTING METHOD OF PIXEL CIRCUIT, DRIVING METHOD OF DISPLAY PANEL AND DISPLAY DEVICE BOE TECHNOLOGY GROUP CO., LTD. (CN) 2023-06-29 US disclosed
CN-114989295-B anti-MERS-CoV monoclonal antibody and application thereof 上海优晶生物科技有限公司 2023-05-23 CN disclosed
CN-114538512-A Luminescent vanadium tetrasulfide, preparation method and application thereof 太原理工大学 2022-05-27 CN disclosed
CN-113595627-B Optical power calibration method based on space linear superposition principle 中国电子技术标准化研究院 2022-05-17 CN disclosed
US-20190070165-A1 N-HYDROXYISOQUINOLINEDIONE INHIBITORS OF HBV REPLICATION SAINT LOUIS UNIVERSITY (US) 2019-03-07 US disclosed
WO-2017161133-A1 N-HYDROXYISOQUINOLINEDIONE INHIBITORS OF HBV REPLICATION SAINT LOUIS UNIVERSITY (US) 2017-09-21 WO disclosed
WO-2012085003-A1 2-HYDROXYISOQUINOLINE-1,3(2H,4H)-DIONES AND RELATED COMPOUNDS USEFUL AS HIV REPLICATION INHIBITORS KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) 2012-06-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190070165-A1 N-HYDROXYISOQUINOLINEDIONE INHIBITORS OF HBV REPLICATION HCCS, HAVCR2, HDGF KCNK3 4833/4885KCNK9 4821/4885NPC1 852/4885
US-20260026340-A1 STACKED SEMICONDUCTOR DEVICE KCNQ4, KCNQ5, VDAC1 KCNK3 114/4885KCNK9 51/4885NPC1 3728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.