Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | MAP2 | P11137 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512459 | 0.71 | CTNNB1 (0.45) | CTNNB1CYP1A2CYP2C9CYP2C19PLA2G10 | |
| SCHEMBL29193018 | 0.70 | RAB9A (0.51) | MEN1KMT2ACTNNB1PLA2G10F10 | |
| SCHEMBL16670658 | 0.69 | BTK (0.53) | MEN1KMT2AF10CHEK2BTK | |
| Hydrochloric Acid SCHEMBL16670477 | 0.68 | BTK (0.53) | MEN1KMT2AF10CHEK2BTK | |
| SCHEMBL21596337 | 0.68 | PIN1 (0.55) | MEN1KMT2ACTNNB1CYP1A2POLB | |
| SCHEMBL16670718 | 0.68 | BTK (0.53) | MEN1KMT2ACTNNB1PLA2G10F10 | |
| SCHEMBL31214767 | 0.67 | NCOA1 (0.59) | POLBDHODHIKBKB | |
| Diphenylether SCHEMBL23068684 | 0.67 | CTNNB1 (0.74) | KMT2ACTNNB1CHEK2PARP10SIRT2 | |
| SCHEMBL920637 | 0.66 | PARP10 (0.56) | KMT2ACTNNB1POLBCYP2C9CYP2C19 | |
| SCHEMBL742272 | 0.66 | RAB9A (0.75) | KMT2ACTNNB1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655330-A1 | SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS | Purdue Pharma LP (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012085650-A1 | SUBSTITUTED PYRIDINES AS SODIUM CHANNEL BLOCKERS | PURDUE PHARMA L.P. (US) | 2012-06-28 | — | — | WO | disclosed |