Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.30 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12660123 | 0.77 | MAPK14 (0.32) | MAPK14 | |
| Hydrochloric Acid SCHEMBL1839866 | 0.69 | GABRA1 (0.34) | MAPK14 | |
| SCHEMBL1076783 | 0.66 | TP53 (0.45) | PTGS2ALDH1A1GAA | |
| SCHEMBL12658858 | 0.65 | KDM4E (0.38) | PTGS2 | |
| SCHEMBL19327459 | 0.64 | MAPK14 (0.40) | MAPK14ALDH1A1 | |
| SCHEMBL692691 | 0.64 | PKM (0.33) | PKMGAA | |
| SCHEMBL1075638 | 0.62 | MAPT (0.51) | MAPK14ALDH1A1 | |
| SCHEMBL15716473 | 0.61 | SMN1; SMN2 (0.47) | ALDH1A1 | |
| SCHEMBL20731985 | 0.61 | DRD2 (0.40) | MAPK14ALDH1A1GAA | |
| SCHEMBL14592096 | 0.59 | MAPK14 (0.43) | MAPK14PTGS2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084472-A1 | PROCESS FOR DYEING KERATIN FIBRES USING HYDROXYBENZALDEHYDE DERIVATIVES, OXIDIZING AGENTS AND ALKALINIZING AGENTS IN THE PRESENCE OF HEAT | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |