Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | WNT3A | P56704 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20819374 | 0.83 | CTNNB1 (0.49) | CTNNB1WNT3ANPC1RAB9AMAPT | |
| SCHEMBL2380013 | 0.81 | CTNNB1 (0.48) | CTNNB1WNT3ANPC1RAB9AMAPT | |
| Bromide SCHEMBL6111604 | 0.80 | CTNNB1 (0.47) | CTNNB1WNT3ANPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL6110118 | 0.80 | CTNNB1 (0.47) | CTNNB1WNT3ANPC1RAB9AMAPT | |
| SCHEMBL10558229 | 0.80 | CTNNB1 (0.44) | CTNNB1WNT3ANPC1RAB9AMAPT | |
| SCHEMBL5312789 | 0.79 | BRD4 (0.43) | CTNNB1WNT3ANPC1RAB9AMAPT | |
| SCHEMBL8237045 | 0.79 | EGLN2 (0.51) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL14697792 | 0.79 | BRD4 (0.48) | CTNNB1WNT3ANPC1RAB9AMAPT | |
| SCHEMBL15988841 | 0.79 | CTNNB1 (0.56) | CTNNB1WNT3ANPC1RAB9AMAPT | |
| SCHEMBL365395 | 0.79 | ALDH1A1 (0.45) | CTNNB1WNT3ANPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3324977-B1 | BENZODIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARM INC (US) | 2022-07-13 | — | — | EP | disclosed |
| EP-3202761-B1 | PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2022-03-16 | — | — | EP | disclosed |
| CN-107074779-B | Pyridazine compounds | 住友化学株式会社 | 2020-05-01 | — | — | CN | disclosed |
| US-9924719-B2 | Pyridazine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-03-27 | — | — | US | disclosed |
| US-20170295787-A1 | PYRIDAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-19 | — | — | US | disclosed |
| EP-3202761-A1 | PYRIDAZINE COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2017-08-09 | — | — | EP | disclosed |
| US-20120157488-A1 | ARYL-AND HETEROARYLCARBONYL DERIVATIVES OF HEXAHYDROINDENOPYRIDINE AND OCTAHYDROBENZOQUINOLINE | BOEHRINGER-INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | US | disclosed |
| US-20120157488-A1 | ARYL-AND HETEROARYLCARBONYL DERIVATIVES OF HEXAHYDROINDENOPYRIDINE AND OCTAHYDROBENZOQUINOLINE | BOEHRINGER-INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157488-A1 | ARYL-AND HETEROARYLCARBONYL DERIVATIVES OF HEXAHYDROINDENOPYRIDINE AND OCTAHYDROBENZOQUINOLINE | HSD17B1, HSD3B1, HSD11B1 | CTNNB1 1836/4885WNT3A 3177/4885NPC1 243/4885 |
| US-20170295787-A1 | PYRIDAZINE COMPOUND | C5, C3AR1, H1-3 | CTNNB1 2095/4885WNT3A 1328/4885NPC1 2335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.