Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.36 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9970790 | 0.86 | ASH1L (0.38) | MAPTKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL9936724 | 0.84 | ASH1L (0.41) | MAPTMEN1ALDH1A1KMT2AASH1L | |
| SCHEMBL9970789 | 0.83 | HTR1B (0.41) | KDM4EALDH1A1GAAASH1L | |
| SCHEMBL9964964 | 0.83 | ROCK2 (0.44) | KDM4ENOS3NOS1 | |
| SCHEMBL9965019 | 0.78 | NOS3 (0.46) | KDM4EMEN1USP2ALDH1A1KMT2A | |
| SCHEMBL6194739 | 0.78 | IDO1 (0.50) | MAPTKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL9965026 | 0.77 | KDM4E (0.38) | KDM4EALDH1A1 | |
| SCHEMBL9964987 | 0.76 | SMN1; SMN2 (0.46) | KDM4ECYP1A2CYP2C19HSD17B10CYP2D6 | |
| SCHEMBL9965020 | 0.74 | LMNA (0.45) | KDM4EMEN1ALDH1A1POLBHTT | |
| SCHEMBL9964986 | 0.74 | BRD4 (0.49) | MAPTKDM4EMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080288-A1 | 4-AMINOINDOLE DERIVATIVES AND USE THEREOF FOR THE OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |