SCHEMBL9966327

SCHEMBL9966327

OC1OC2OC2C(O)C1O

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
TSHR P16473 2/20 0.44
LMNA P02545 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
GBA1 P04062 2/20 0.42
TXNRD1 Q16881 2/20 0.40
TXNRD3 Q86VQ6 2/20 0.40
TXNRD2 Q9NNW7 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22037294 1.00 ALDH1A1 (0.44) ALDH1A1TSHRLMNATDP1GBA1
SCHEMBL3787675 0.76
SCHEMBL19736584 0.75 ALDH1A1 (0.44) ALDH1A1TSHRLMNATDP1GBA1
SCHEMBL12957660 0.75 ALDH1A1 (0.50) ALDH1A1TSHRLMNATDP1GBA1
SCHEMBL16016300 0.73 ALDH1A1 (0.67) ALDH1A1TSHRLMNATDP1TXNRD1
SCHEMBL890314 0.73 ALDH1A1 (0.67) ALDH1A1TSHRLMNATDP1TXNRD1
SCHEMBL18736267 0.73 ALDH1A1 (0.67) ALDH1A1TSHRLMNATDP1TXNRD1
SCHEMBL4911680 0.73 ALDH1A1 (0.67) ALDH1A1TSHRLMNATDP1TXNRD1
SCHEMBL6450045 0.73 ALDH1A1 (0.67) ALDH1A1TSHRLMNATDP1TXNRD1
SCHEMBL4911675 0.73 ALDH1A1 (0.67) ALDH1A1TSHRLMNATDP1TXNRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220152196-A1 SAPONIN-BASED VACCINE ADJUVANTS THE UAB RESEARCH FOUNDATION 2022-05-19 US disclosed
EP-2561085-B1 CELL-BASED PRODUCTION OF NONULOSONATES NAT RES COUNCIL CANADA (CA) 2019-08-14 EP disclosed
US-20190127411-A1 GLYCOLIPOPEPTIDE BIOSURFACTANTS CRODA INTERNATIONAL PLC (GB) 2019-05-02 US disclosed
US-9512455-B2 Cell-based production of nonulosonates NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2016-12-06 US disclosed
US-20160022826-A1 CARBOHYDRATE-MODIFIED GLYCOPROTEINS AND USES THEREOF LUMOS PHARMA, INC. 2016-01-28 US disclosed
US-20140356912-A1 CELL-BASED PRODUCTION OF NONULOSONATES UNIVERSITY OF OTTAWA (CA) 2014-12-04 US disclosed
US-8841099-B2 Cell-based production of nonulosonates NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2014-09-23 US disclosed
WO-2014077960-A1 SYNTHESIS OF CARBOHYDRATE-BASED SURFACTANTS THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2014-05-22 WO disclosed
US-20130196381-A1 CELL-BASED PRODUCTION OF NANULOSONATES UNIVERSITY OF OTTAWA (CA) 2013-08-01 US disclosed
WO-2012082635-A1 SYNTHETIC OLIGOSACCHARIDE GROUP A STREPTOCOCCUS ANCORA PHARMACEUTICALS, INC. (US) 2012-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190127411-A1 GLYCOLIPOPEPTIDE BIOSURFACTANTS LYPLAL1, LNPEP, PHOSPHO1 ALDH1A1 4821/4885TSHR 4094/4885LMNA 1526/4885
US-20220152196-A1 SAPONIN-BASED VACCINE ADJUVANTS ST3GAL3, B3GAT3, CSGALNACT1 ALDH1A1 4710/4885TSHR 3151/4885LMNA 4314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.