Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966449 | 0.80 | MAP4K4 (0.33) | MAP4K4HDAC1 | |
| SCHEMBL9966448 | 0.72 | MAP4K4 (0.35) | MAP4K4HDAC1 | |
| SCHEMBL9966380 | 0.72 | PIK3CA (0.33) | MAP4K4HDAC1 | |
| SCHEMBL14244013 | 0.68 | HPGD (0.41) | MAP4K4HDAC1 | |
| SCHEMBL9966514 | 0.68 | MAP4K4 (0.40) | MAP4K4HDAC1 | |
| SCHEMBL9966472 | 0.66 | IDO1 (0.40) | MAP4K4HDAC1 | |
| SCHEMBL9966385 | 0.66 | MAP4K4 (0.44) | MAP4K4HDAC1 | |
| SCHEMBL9966389 | 0.66 | ALOX5 (0.41) | MAP4K4HDAC1 | |
| SCHEMBL9966467 | 0.65 | ALOX5AP (0.40) | MAP4K4 | |
| SCHEMBL9966365 | 0.65 | USP2 (0.33) | MAP4K4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082817-A1 | BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |