Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9966380 | 0.91 | PIK3CA (0.33) | MAP4K4USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9966514 | 0.88 | MAP4K4 (0.40) | MAP4K4USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9966365 | 0.85 | USP2 (0.33) | MAP4K4USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9966413 | 0.82 | RIPK1 (0.37) | MAP4K4 | |
| SCHEMBL9966308 | 0.82 | ALOX5AP (0.33) | — | |
| SCHEMBL9966486 | 0.81 | MAP4K4 (0.33) | MAP4K4USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9966523 | 0.80 | IDO1 (0.36) | MAP4K4 | |
| SCHEMBL9966375 | 0.80 | MAP4K4 (0.34) | MAP4K4HDAC1 | |
| SCHEMBL14244013 | 0.77 | HPGD (0.41) | MAP4K4USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9966277 | 0.77 | ALOX5AP (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082817-A1 | BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |