Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13106304 | 0.88 | MEN1 (0.56) | MEN1ALDH1A1CYP2D6RAB9AKMT2A | |
| SCHEMBL17935500 | 0.87 | ALDH1A1 (0.65) | MEN1ALDH1A1CYP2D6RAB9AKMT2A | |
| SCHEMBL9936379 | 0.79 | NPC1 (0.57) | MEN1CYP2D6RAB9AKMT2AABL1 | |
| SCHEMBL23428585 | 0.74 | NPY1R (0.49) | MEN1RAB9AKMT2AMAPT | |
| SCHEMBL29779708 | 0.73 | CA12 (0.59) | CYP2D6 | |
| SCHEMBL19809314 | 0.73 | CA12 (0.59) | CYP2D6 | |
| SCHEMBL25196801 | 0.73 | ABCG2 (0.60) | HRH3MAPT | |
| SCHEMBL25205827 | 0.73 | ABCG2 (0.60) | HRH3MAPT | |
| SCHEMBL8097555 | 0.70 | RAB9A (1.00) | MEN1ALDH1A1CYP2D6RAB9AKMT2A | |
| SCHEMBL29919785 | 0.70 | CA12 (0.56) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012079154-A1 | SELECTIVE ESTROGEN RECEPTOR MODULATORS | DALHOUSIE UNIVERSITY (CA) | 2012-06-21 | — | — | WO | disclosed |