Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995898 | 0.89 | HPGD (0.53) | KDM4EALDH1A1HSD17B10LMNANPC1 | |
| SCHEMBL1278933 | 0.86 | SMN1; SMN2 (0.53) | KDM4EALDH1A1HSD17B10NPC1RAB9A | |
| SCHEMBL10373392 | 0.83 | ALDH1A1 (0.45) | KDM4EALDH1A1HSD17B10LMNAALOX15 | |
| SCHEMBL997070 | 0.80 | TUBB4A (0.46) | KDM4EALDH1A1HSD17B10LMNAALOX15 | |
| SCHEMBL997661 | 0.80 | TUBB4A (0.46) | KDM4EALDH1A1HSD17B10LMNAALOX15 | |
| SCHEMBL11445268 | 0.79 | CA9 (0.42) | KDM4EALDH1A1HSD17B10LMNAALOX15 | |
| SCHEMBL1494271 | 0.79 | RXFP1 (0.46) | KDM4EALDH1A1HSD17B10LMNANPC1 | |
| SCHEMBL20630769 | 0.78 | HTT (0.68) | KDM4EALDH1A1HSD17B10LMNARAB9A | |
| SCHEMBL997838 | 0.76 | TUBB4A (0.59) | KDM4EALDH1A1HSD17B10LMNANPC1 | |
| SCHEMBL996876 | 0.76 | TUBB4A (0.59) | KDM4EALDH1A1HSD17B10LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |