Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996699 | 0.89 | KDM4E (0.54) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL6215960 | 0.86 | HPGD (0.53) | HPGDLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL11375094 | 0.84 | LMNA (0.51) | HPGDLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL8569614 | 0.84 | ALDH1A1 (0.57) | HPGDLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL8573958 | 0.80 | LMNA (0.47) | HPGDLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL11367616 | 0.79 | ALDH1A1 (0.52) | HPGDLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL10687082 | 0.79 | NQO1 (0.58) | HPGDLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL20630769 | 0.78 | HTT (0.68) | HPGDLMNAALDH1A1RAB9ATSHR | |
| SCHEMBL5458653 | 0.78 | LMNA (0.64) | HPGDLMNAALDH1A1NPC1RAB9A | |
| SCHEMBL10373392 | 0.77 | ALDH1A1 (0.45) | LMNAALDH1A1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009826-A2 | NOVEL CHALCONE DERIVATIVES WITH CYTOTOXIC ACTIVITY | ADAMED Sp.z o.o. (PL) | 2011-01-27 | — | — | WO | disclosed |