Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 3/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL996296 | 0.94 | CYP1A2 (0.38) | CA12CA9ALDH1A1MAPTHPGD | |
| SCHEMBL11787190 | 0.74 | MEN1 (0.35) | ALDH1A1MAPTHPGDCYP1A2MEN1 | |
| SCHEMBL5283198 | 0.70 | ALDH1A1 (0.41) | CA12CA9ALDH1A1MAPTHPGD | |
| SCHEMBL3646721 | 0.68 | MGAM (0.41) | CA12CA9ALDH1A1MAPTNCF1 | |
| SCHEMBL6307826 | 0.68 | NCF1 (0.47) | CA12CA9ALDH1A1MAPTHPGD | |
| SCHEMBL5894508 | 0.68 | ALDH1A1 (0.39) | CA12CA9ALDH1A1MAPTHPGD | |
| SCHEMBL28614872 | 0.68 | ALDH1A1 (0.39) | CA12CA9ALDH1A1MAPTHPGD | |
| SCHEMBL14409806 | 0.65 | NCF1 (0.48) | CA12CA9ALDH1A1MAPTHPGD | |
| SCHEMBL22144095 | 0.63 | MAPT (0.37) | ALDH1A1MAPTCYP1A2MGAMHDAC8 | |
| SCHEMBL22144248 | 0.63 | NCF1 (0.36) | CA12CA9ALDH1A1MAPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355308-A | Providing a completely oncogenic reversed anticancer drug obtained by repositioning the drug interacting with a target designated as unchanged checkpoint carried by a tumor cell GPCR | 加尔巴亚·斯盖伊 | 2024-01-05 | — | — | CN | claimed |
| WO-2012120206-A1 | NOVEL DIHYDRO-OXAZOLOBENZODIAZEPINONE DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2012-09-13 | — | — | WO | claimed |
| US-20070098631-A2 | DIAGNOSTIC COMPOUNDS COMPRISING A SCAFFOLD COUPLED TO A SIGNAL ENTITY FOR MEDICAL IMAGING DIAGNOSTIC | GUERBET (FR) | 2007-05-03 | — | — | US | claimed |
| US-20050260127-A1 | Diagnostic compounds comprising a scaffold coupled to a signal entity for medical imaging diagnostic | GUERBET (FR) | 2005-11-24 | — | — | US | claimed |
| EP-1212306-A2 | HYDROXYALKANOYLAMINOLACTAMS AND RELATED STRUCTURES AS INHIBITORS OF ABETA PROTEIN PRODUCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-06-12 | — | — | EP | claimed |
| EP-1089980-A1 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | Elan Pharmaceuticals, Inc. (US) | 2001-04-11 | — | — | EP | claimed |
| WO-2001019797-A2 | HYDROXYALKANOYL AMINOLACTAMS AND RELATED STRUCTURES AS INHIBITORS OF Aβ PROTEIN PRODUCTION | DU PONT PHARMACEUTICALS COMPANY (US) | 2001-03-22 | — | — | WO | claimed |
| WO-1999067221-A1 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | ELAN PHARMACEUTICALS, INC. (US) | 1999-12-29 | — | — | WO | claimed |
| EP-0038423-B1 | METHOD FOR THE PREPARATION OF BENZODIAZEPINE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-11-21 | — | — | EP | claimed |
| US-4335042-A | Process to produce imidazobenzodiazepine intermediates | HOFFMANN-LA ROCHE INC. (US) | 1982-06-15 | — | — | US | claimed |
| EP-0038423-A1 | Method for the preparation of benzodiazepine derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-10-28 | — | — | EP | claimed |
| JP-3027365-A | — | — | None | — | — | JP | disclosed |
| JP-3027364-A | — | — | None | — | — | JP | disclosed |
| JP-54090188-A | — | — | None | — | — | JP | disclosed |
| CN-117355308-A | Providing a completely oncogenic reversed anticancer drug obtained by repositioning the drug interacting with a target designated as unchanged checkpoint carried by a tumor cell GPCR | 加尔巴亚·斯盖伊 | 2024-01-05 | — | — | CN | disclosed |
| US-4151285-A | ANTICONVULSANT, ANTI-ANXIETY AGENTS | A. H. ROBINS COMPANY, INC. (US) | 1979-04-24 | — | — | US | disclosed |
| US-4110337-A | ANALGESIC, ANTIINFLAMMATORY | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1978-08-29 | — | — | US | disclosed |
| US-4105852-A | ANTICONVULSANTS, MUSCLE RELAXANTS, SEDATIVES | HOFFMANN-LA ROCHE INC. (US) | 1978-08-08 | — | — | US | disclosed |
| US-4044003-A | Process for preparing 1,4-benzodiazepines | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-08-23 | — | — | US | disclosed |
| US-3886214-A | Benzodiazepin-2-ones and processes for the preparation thereof | HOFFMANN LA ROCHE | 1975-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050260127-A1 | Diagnostic compounds comprising a scaffold coupled to a signal entity for medical imaging diagnostic | CHRM1, BRD4, KCNJ2 | CA12 3392/4885CA9 3952/4885ALDH1A1 702/4885 |
| US-20070098631-A2 | DIAGNOSTIC COMPOUNDS COMPRISING A SCAFFOLD COUPLED TO A SIGNAL ENTITY FOR MEDICAL IMAGING DIAGNOSTIC | HTR3D, BRD4, CNR1 | CA12 3075/4885CA9 3838/4885ALDH1A1 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.