Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | NCF1 | P14598 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996754 | 0.94 | CA12 (0.41) | CYP1A2CA12CA9MGAMALDH1A1 | |
| SCHEMBL11787190 | 0.69 | MEN1 (0.35) | CYP1A2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL3646721 | 0.68 | MGAM (0.41) | CYP1A2CA12CA9MGAMALDH1A1 | |
| SCHEMBL5283198 | 0.65 | ALDH1A1 (0.41) | CYP1A2CA12CA9MGAMALDH1A1 | |
| SCHEMBL6307826 | 0.64 | NCF1 (0.47) | CYP1A2CA12CA9MGAMALDH1A1 | |
| SCHEMBL28614872 | 0.64 | ALDH1A1 (0.39) | CYP1A2CA12CA9MGAMALDH1A1 | |
| SCHEMBL5894508 | 0.64 | ALDH1A1 (0.39) | CYP1A2CA12CA9MGAMALDH1A1 | |
| SCHEMBL22144095 | 0.63 | MAPT (0.37) | CYP1A2MGAMALDH1A1MAPTKDM4E | |
| Quinoline SCHEMBL1591955 | 0.63 | ALDH1A1 (0.85) | CYP1A2ALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL14409806 | 0.61 | NCF1 (0.48) | CYP1A2CA12CA9MGAMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2273993-A1 | METHODS AND COMPOSITIONS FOR THE INTRACEREBROVENTRICULAR ADMINISTRATION OF FELBAMATE | The Regents of the University of Colorado, A Body Corporate (US) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009151741-A1 | METHODS AND COMPOSITIONS FOR THE INTRACEREBROVENTRICULAR ADMINISTRATION OF FELBAMATE | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2009-12-17 | — | — | WO | disclosed |