Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ARG1 | P05089 | 9/20 | 0.44 |
| ▸ | ARG2 | P78540 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831414 | 1.00 | ODC1 (1.00) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL3831417 | 1.00 | ODC1 (1.00) | ODC1LMNABLMKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL9586259 | 0.98 | ODC1 (0.96) | ODC1LMNABLMKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL9586263 | 0.98 | ODC1 (0.96) | ODC1LMNABLMKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL10778576 | 0.98 | ODC1 (0.96) | ODC1LMNABLMKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL10556045 | 0.96 | ODC1 (0.92) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL7204384 | 0.94 | ODC1 (0.88) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL7204381 | 0.94 | ODC1 (0.88) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL7198360 | 0.80 | ODC1 (0.67) | ODC1LMNABLMKDM4EMAPT | |
| SCHEMBL7198367 | 0.80 | ODC1 (0.67) | ODC1LMNABLMKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2943189-A1 | METHODS AND COMP0STIONS FOR TREATMENT OF DEMYELINATING DISEASES | Pathologica LLC (US) | 2015-11-18 | — | — | EP | disclosed |
| WO-2014110154-A1 | METHODS AND COMP0STIONS FOR TREATMENT OF DEMYELINATING DISEASES | PATHOLOGICA LLC (US) | 2014-07-17 | — | — | WO | disclosed |
| EP-2453886-A2 | PHARMACEUTICAL FOR ORAL DELIVERY COMPRISING MGBG AND METHODS OF TREATING DISEASE | Pathologica, LLC. (US) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011009039-A2 | PHARMACEUTICAL FOR ORAL DELIVERY COMPRISING MGBG AND METHODS OF TREATING DISEASE | PATHOLOGICA LLC (US) | 2011-01-20 | — | — | WO | disclosed |
| WO-2009112505-A2 | PLANTS HAVING IMPROVED RESISTANCE TO PATHOGENS | BIOGEMMA (FR) | 2009-09-17 | — | — | WO | disclosed |
| EP-2100962-A1 | Plants having improved resistance to pathogens | Biogemma (FR) | 2009-09-16 | — | — | EP | disclosed |
| US-20080096974-A2 | Polyamine-Metal Chelator Conjugates | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2008-04-24 | — | — | US | disclosed |
| WO-2007109178-A2 | INDOLE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | PHARMACYCLICS, INC. (US) | 2007-09-27 | — | — | WO | disclosed |
| US-20060211773-A1 | Polyamine-metal chelator conjugates | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2006-09-21 | — | — | US | disclosed |
| EP-1667727-A2 | POLYAMINE-METAL CHELATOR CONJUGATES | University of Florida Research Foundation, Inc. (US) | 2006-06-14 | — | — | EP | disclosed |
| EP-0357029-A2 | Method for the production of (-) 2-difluoromethyl-ornithine | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-03-07 | — | — | EP | disclosed |
| US-4866206-A | INHIBITORS OF ORNITHINE DECARBOXYLASE | MERRELL DOW FRANCE ET CIE (FR) | 1989-09-12 | — | — | US | disclosed |
| US-4743691-A | INHIBITORS OF ORNITHINE DECARBOXYLASE | MERRELL DOW FRANCE ET CIE (FR) | 1988-05-10 | — | — | US | disclosed |
| US-4695588-A | DECARBOXYLASE INHIBITORS | MERCK & CO., INC. (US) | 1987-09-22 | — | — | US | disclosed |
| EP-0046710-B1 | PREPARATION OF AMINOACETONITRILE DERIVATIVES | MERRELL TORAUDE ET COMPAGNIE (FR) | 1984-06-13 | — | — | EP | disclosed |
| US-4405530-A | Process for preparing fluorinated amino-nitriles | MERRELL TORAUDE ET COMPAGNIE (FR) | 1983-09-20 | — | — | US | disclosed |
| US-4325961-A | FLUOROMETHYLHISTIDINE, ESTERS, AND SALTS | MERCK & CO., INC. (US) | 1982-04-20 | — | — | US | disclosed |
| EP-0046710-A1 | Preparation of aminoacetonitrile derivatives | MERRELL TORAUDE ET COMPAGNIE (FR) | 1982-03-03 | — | — | EP | disclosed |
| US-4288601-A | A-FLUOROMETHYL AMINO ACIDS FROM THE A-HYDROXYMETHYL COMPOUND USING SULFUR TETRAFLUORIDE AND BORON TRIFLUORIDE IN HYDROFLUORIC ACID | MERCK & CO., INC. (US) | 1981-09-08 | — | — | US | disclosed |
| US-4215221-A | A-FLUOROMETHYL AMINO ACIDS FROM THE A-HYDROXYMETHYL COMPOUNDS USING SULFUR TETRAFLUORIDE IN HYDROFLUORIC ACID AND ALUMINUM CHLORIDE | MERCK & CO., INC. (US) | 1980-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211773-A1 | Polyamine-metal chelator conjugates | SLC40A1, SLC7A1, CATSPER1 | ODC1 369/4885LMNA 1579/4885BLM 3506/4885 |
| US-20080096974-A2 | Polyamine-Metal Chelator Conjugates | SLC7A1, SLC40A1, SRM | ODC1 121/4885LMNA 1556/4885BLM 3868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.