SCHEMBL9968258

SCHEMBL9968258

CCC(C)c1cc2c(cn1)c1cnc([Si](C)(C)c3cc4c(cn3)c3cnc(C(C)CC)cc3n4-c3ccccc3-c3ccccc3)cc1n2-c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9968054 0.68 CDK4 (0.40)
SCHEMBL9968146 0.68 MEN1 (0.33) SMN1; SMN2
SCHEMBL9968270 0.68 DHFR (0.35)
SCHEMBL9968215 0.67 NFATC1 (0.30)
SCHEMBL9968051 0.66 KDM4E (0.42) HPGD
SCHEMBL9968104 0.64
SCHEMBL9968151 0.64 ALDH1A1 (0.36) HPGDSMN1; SMN2
SCHEMBL24356776 0.64 L3MBTL1 (0.58)
SCHEMBL28453269 0.63 L3MBTL1 (0.67)
SCHEMBL24356777 0.62 L3MBTL1 (0.56)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20120153817-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed