Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9968581 | 0.90 | KDM4E (0.43) | MAPK1LMNARAB9AKDM4EALDH1A1 | |
| SCHEMBL9941253 | 0.84 | KMT2A (0.59) | LMNAALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL9968024 | 0.83 | SLC6A2 (0.45) | RAB9AKMT2APOLBMEN1SLC6A2 | |
| SCHEMBL9968585 | 0.82 | PKM (0.50) | ALDH1A1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9968618 | 0.82 | KMT2A (0.47) | MAPK1LMNARAB9AKDM4EALDH1A1 | |
| SCHEMBL9968023 | 0.81 | SLC6A2 (0.41) | MAPK1RAB9AALDH1A1KMT2APOLB | |
| SCHEMBL9968571 | 0.79 | SLC22A12 (0.43) | SLC6A2SLC6A4SLC6A3NAMPT | |
| SCHEMBL9968477 | 0.78 | ALDH1A1 (0.43) | MAPK1LMNARAB9AKDM4EALDH1A1 | |
| SCHEMBL9941527 | 0.76 | TSHR (0.60) | LMNAALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL15609395 | 0.73 | MAPT (0.60) | LMNAALDH1A1KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012082862-A2 | ANDROGEN RECEPTOR INHIBITORS AND METHODS OF USE THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2012-06-21 | — | — | WO | disclosed |