Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9968851 | 0.90 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1SMN1; SMN2LMNA | |
| SCHEMBL16530178 | 0.89 | MAPK1 (0.57) | ALDH1A1TSHRMAPK1SMN1; SMN2LMNA | |
| SCHEMBL9969790 | 0.87 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPK1SMN1; SMN2LMNA | |
| SCHEMBL9937438 | 0.86 | ALDH1A1 (0.39) | ALDH1A1TSHRMAPK1SMN1; SMN2LMNA | |
| SCHEMBL9969477 | 0.86 | MAPK1 (0.59) | ALDH1A1TSHRMAPK1SMN1; SMN2LMNA | |
| SCHEMBL9938471 | 0.85 | CYP19A1 (0.41) | ALDH1A1TSHRMAPK1SMN1; SMN2LMNA | |
| SCHEMBL15341257 | 0.84 | TYR (0.40) | ALDH1A1TSHRLMNAMAPTKMT2A | |
| SCHEMBL9936598 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPK1SMN1; SMN2LMNA | |
| SCHEMBL9936951 | 0.83 | TYR (0.44) | ALDH1A1TSHRMAPK1SMN1; SMN2LMNA | |
| SCHEMBL9937177 | 0.82 | L3MBTL1 (0.40) | ALDH1A1TSHRMAPK1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | claimed |
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2013-10-24 | — | — | US | claimed |
| EP-2651886-B1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | ORÉAL L (FR) | 2015-03-04 | — | — | EP | disclosed |
| EP-2651886-B1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | ORÉAL L (FR) | 2015-03-04 | — | — | EP | disclosed |
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | disclosed |
| US-8937187-B2 | Method for depigmenting keratin materials using resorcinol derivatives | L'OREAL (FR) | 2015-01-20 | — | — | US | disclosed |
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2013-10-24 | — | — | US | disclosed |
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2013-10-24 | — | — | US | disclosed |
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2013-10-24 | — | — | US | disclosed |
| WO-2012079938-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | L'OREAL (FR) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281507-A1 | METHOD FOR DEPIGMENTING KERATIN MATERIALS USING RESORCINOL DERIVATIVES | KRT18, KLHL20, IK | ALDH1A1 222/4885TSHR 4359/4885MAPK1 3021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.