Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11788237 | 0.87 | KCNH3 (0.61) | APPGAACA1CA2CA9 | |
| SCHEMBL9970375 | 0.86 | ALDH1A1 (0.62) | APPBCHEACHEGAACA1 | |
| SCHEMBL1562297 | 0.83 | APP (0.59) | APPGAACA1CA2CA9 | |
| SCHEMBL28736402 | 0.82 | LMNA (0.60) | APPBCHEACHEGAACA1 | |
| SCHEMBL11750440 | 0.80 | ALDH1A1 (0.44) | APPBCHEACHEGAATDP1 | |
| SCHEMBL7896995 | 0.79 | CASR (0.59) | KCNH3LMNAALDH1A1 | |
| SCHEMBL18276656 | 0.79 | GAA (0.66) | APPGAANPSR1 | |
| SCHEMBL15720720 | 0.78 | KCNH3 (0.56) | APPGAACA1CA2CA9 | |
| SCHEMBL1924308 | 0.78 | KCNH3 (0.83) | GAATDP1KCNH3LMNAPOLB | |
| SCHEMBL30568861 | 0.78 | KCNH3 (0.83) | GAATDP1KCNH3LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083190-A1 | INSECT ODORANT RECEPTOR ANTAGONISTS | THE ROCKEFELLER UNIVERSITY (US) | 2012-06-21 | — | — | WO | disclosed |