Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.59 |
| ▸ | PDE5A | O76074 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | RAD52 | P43351 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11788237 | 0.96 | KCNH3 (0.61) | APPPDE5ACA12CA1CA2 | |
| SCHEMBL10055023 | 0.89 | CA9 (0.68) | CA12CA1CA2CA9CA14 | |
| SCHEMBL20511399 | 0.89 | CA12 (0.55) | APPPDE5ACA12CA1CA2 | |
| SCHEMBL18276656 | 0.87 | GAA (0.66) | APPPDE5AGAANPSR1 | |
| SCHEMBL28736402 | 0.87 | LMNA (0.60) | APPPDE5ACA1CA2CA9 | |
| SCHEMBL5273353 | 0.84 | LMNA (0.58) | APPPDE5ACA12CA1CA2 | |
| SCHEMBL20511185 | 0.84 | APP (0.48) | APPPDE5ACA12CA1CA2 | |
| SCHEMBL3298289 | 0.84 | KCNH3 (0.73) | APPKCNH3LMNARAD52GAA | |
| SCHEMBL11866701 | 0.83 | CA12 (0.62) | APPCA12CA1CA2CA9 | |
| SCHEMBL15720720 | 0.83 | KCNH3 (0.56) | APPPDE5ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827920-B2 | Nanostructure, a biosensor including the nanostructure, and a screening method | POSTECH Research and Business Development Foundation (KR) | 2023-11-28 | — | — | US | disclosed |
| US-11827920-B2 | Nanostructure, a biosensor including the nanostructure, and a screening method | POSTECH Research and Business Development Foundation (KR) | 2023-11-28 | — | — | US | disclosed |
| CN-108191774-B | Heterocyclic compound, preparation method and application thereof | 中国药科大学 | 2022-05-24 | — | — | CN | disclosed |
| WO-2020146779-A1 | mTORC1 INHIBITORS FOR ACTIVATING AUTOPHAGY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-16 | — | — | WO | disclosed |
| WO-2018175958-A1 | THIOREDOXIN MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-09-27 | — | — | WO | disclosed |
| US-20170020900-A1 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | NIH - DEITR | 2017-01-26 | — | — | US | disclosed |
| US-20170020900-A1 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | NIH - DEITR | 2017-01-26 | — | — | US | disclosed |
| US-9301940-B2 | Methods for screening antimicrobial and antiviral compounds and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2016-04-05 | — | — | US | disclosed |
| US-9301940-B2 | Methods for screening antimicrobial and antiviral compounds and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2016-04-05 | — | — | US | disclosed |
| US-20120202814-A1 | COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2012-08-09 | — | — | US | disclosed |
| US-20080146518-A1 | Cationic Lipids for the Transfection of Nucleic Acids | POLITECNICO DI MILANO (IL) | 2008-06-19 | — | — | US | disclosed |
| WO-2008066576-A2 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2008-06-05 | — | — | WO | disclosed |
| EP-1846378-A2 | CATIONIC LIPIDS FOR THE TRANSFECTION OF NUCLEIC ACIDS | Politecnico Di Milano (IT) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006087752-A2 | CATIONIC LIPIDS FOR THE TRANSFECTION OF NUCLEIC ACIDS | POLITECNICO DI MILANO (IT) | 2006-08-24 | — | — | WO | disclosed |
| US-4981964-A | PHOTOSTABILIZERS | ICI AMERICAS INC. (US) | 1991-01-01 | — | — | US | disclosed |
| EP-0373892-A1 | Tetramethyl piperidyl terminated triazine oligomeric esters and amides | ICI AMERICAS INC. (US) | 1990-06-20 | — | — | EP | disclosed |
| EP-0373839-A1 | Oligomeric polyesters and polyamides containing dipiperidyl triazine groups | ICI AMERICAS INC. (US) | 1990-06-20 | — | — | EP | disclosed |
| US-4889882-A | RADIATION RESISTANCE, PHOTOSTABILITY POLYMER ADDITIVE | ICI AMERICAS INC. (US) | 1989-12-26 | — | — | US | disclosed |
| US-4874420-A | Herbicidal substituted triazines | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-17 | — | — | US | disclosed |
| US-3931165-A | INSECTICIDES, HERBICIDES | BARER SOL J | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202814-A1 | COMPOUNDS WITH DDX3 INHIBITORY ACTIVITY AND USES THEREOF | DDX3X, DDX21, DDX39B | APP 3458/4885PDE5A 1959/4885CA12 4168/4885 |
| US-20170020900-A1 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | ZC3HAV1, MAVS, EIF2AK2 | APP 4366/4885PDE5A 3126/4885CA12 4842/4885 |
| US-20080146518-A1 | Cationic Lipids for the Transfection of Nucleic Acids | AARS1, HARS1, LPAR3 | APP 2852/4885PDE5A 4495/4885CA12 4624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.