SCHEMBL9971869

SCHEMBL9971869

c1ccc(-c2cccc(N(c3cccc(-c4ccccc4)c3)c3c4ccccc4c(N(c4cccc(-c5ccccc5)c4)c4cccc(-c5ccccc5)c4)c4ccccc34)c2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 2/20 0.41
MAOA P21397 1/20 0.40
HDAC4 P56524 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
ALDH1A1 P00352 1/20 0.38
KMO O15229 1/20 0.35
ACMSD Q8TDX5 2/20 0.35
ALOX5 P09917 1/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
JAK2 O60674 2/20 0.34
NISCH Q9Y2I1 1/20 0.34
HTR1A P08908 1/20 0.34
HTR7 P34969 1/20 0.34
DHFR P00374 1/20 0.33
HNF4A P41235 1/20 0.33
MCL1 Q07820 1/20 0.33
AGXT P21549 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9971871 0.98 MGLL (0.39) MGLLMAOAHDAC4HDAC2HDAC8
SCHEMBL9971939 0.98 MGLL (0.39) MGLLMAOAHDAC4HDAC2HDAC8
SCHEMBL14446783 0.94 MGLL (0.37) MGLLMAOAHDAC4HDAC2HDAC8
SCHEMBL19817603 0.91 ALDH1A1 (0.38) MGLLMAOAHDAC4HDAC2HDAC8
SCHEMBL14867176 0.90 JAK2 (0.39) MGLLMAOAHDAC4HDAC2HDAC8
SCHEMBL20403905 0.89 MGLL (0.34) MGLLMAOAHDAC4HDAC2HDAC8
SCHEMBL16305280 0.88 CETP (0.37) MGLLHTR1AHTR7AGXT
SCHEMBL14867168 0.88 HSD17B1 (0.39) MGLLHDAC4HDAC2HDAC8ACMSD
SCHEMBL13511249 0.88 CYP2C19 (0.35) MGLLALDH1A1MCL1
SCHEMBL22669636 0.87 MGLL (0.35) MGLLMAOAHDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9136478-B2 Organic light emitting device and display panel using the same method, terminal, and server for implementing fast playout LG DISPLAY CO., LTD. (KR) 2015-09-15 US disclosed
US-9136478-B2 Organic light emitting device and display panel using the same method, terminal, and server for implementing fast playout LG DISPLAY CO., LTD. (KR) 2015-09-15 US disclosed
US-20130092910-A1 ORGANIC LIGHT EMITTING DEVICE AND DISPLAY PANEL USING THE SAME LG DISPLAY CO., LTD. (KR) 2013-04-18 US disclosed
US-20130092910-A1 ORGANIC LIGHT EMITTING DEVICE AND DISPLAY PANEL USING THE SAME LG DISPLAY CO., LTD. (KR) 2013-04-18 US disclosed
US-20120153815-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-21 US disclosed
US-20120153815-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2012-06-21 US disclosed
US-20110175521-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-07-21 US disclosed
US-20110175521-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2011-07-21 US disclosed
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-06-24 US disclosed
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-06-24 US disclosed
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110175521-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 MGLL 3499/4885MAOA 1500/4885HDAC4 1409/4885
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 MGLL 3499/4885MAOA 1500/4885HDAC4 1409/4885
US-20120153815-A1 ORGANIC ELECTROLUMINESCENCE DEVICE ARL1, RIF1, EML4 MGLL 3707/4885MAOA 1025/4885HDAC4 2414/4885
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 MGLL 3499/4885MAOA 1500/4885HDAC4 1409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.