SCHEMBL9971885

SCHEMBL9971885

Cc1ccc(/C=C/c2ccc(Cl)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.60
MAOB P27338 2/20 0.60
NFE2L2 Q16236 5/20 0.58
AHR P35869 1/20 0.58
ALOX5 P09917 2/20 0.57
PTGS1 P23219 2/20 0.57
PTGS2 P35354 2/20 0.57
RELA Q04206 1/20 0.54
MEN1 O00255 1/20 0.51
NPC1 O15118 1/20 0.51
ALDH1A1 P00352 1/20 0.51
CYP3A4 P08684 1/20 0.51
KMT2A Q03164 1/20 0.51
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
KDM4E B2RXH2 1/20 0.48
POLB P06746 1/20 0.48
MAPT P10636 1/20 0.48
RECQL P46063 1/20 0.48
RAB9A P51151 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22485553 1.00 MAOA (0.60) MAOAMAOBNFE2L2AHRALOX5
SCHEMBL11529471 1.00 MAOA (0.60) MAOAMAOBNFE2L2AHRALOX5
SCHEMBL9971855 1.00 MAOA (0.60) MAOAMAOBNFE2L2AHRALOX5
SCHEMBL17367871 0.90 MAOA (0.56) MAOAMAOBNFE2L2AHRALOX5
SCHEMBL8187096 0.87 MAOA (0.50) MAOAMAOBNFE2L2AHRALOX5
SCHEMBL14526489 0.87 MAOA (0.50) MAOAMAOBNFE2L2AHRALOX5
SCHEMBL260347 0.86 AHR (0.74) MAOBNFE2L2AHRALOX5PTGS1
SCHEMBL318786 0.86 NFE2L2 (0.74) NFE2L2ALOX5PTGS1PTGS2RELA
SCHEMBL20582895 0.86 AHR (0.74) MAOBNFE2L2AHRALOX5PTGS1
(E)-1,2-Di-P-Tolylethene SCHEMBL1793692 0.86 NFE2L2 (0.74) NFE2L2ALOX5PTGS1PTGS2RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113443952-B Method for selectively synthesizing cis-olefin and trans-olefin by catalyzing alkyne semi-reduction through iridium with hydrogen supplied by water 南通大学 2022-11-04 CN disclosed
CN-113563150-B Method for selectively synthesizing cis-olefin and trans-olefin by catalyzing alkyne semi-reduction through palladium on hydrogen supplied by water 南通大学 2022-09-02 CN disclosed
CN-109776253-B Method for selectively synthesizing cis-olefin and trans-olefin by catalyzing semi-reduction of alkyne through palladium hydrogen donor by alcohol 南通大学 2022-07-15 CN disclosed
CN-113563150-A Method for selectively synthesizing cis-olefin and trans-olefin by catalyzing alkyne semi-reduction through palladium on hydrogen supplied by water 南通大学 2021-10-29 CN disclosed
CN-113443952-A Method for selectively synthesizing cis-olefin and trans-olefin by catalyzing alkyne semi-reduction through iridium with hydrogen supplied by water 南通大学 2021-09-28 CN disclosed
US-9964869-B2 Triarylamine derivative, electrophotographic photosensitive member, and method for producing electrophotographic photosensitive member KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-05-08 US disclosed
US-9964869-B2 Triarylamine derivative, electrophotographic photosensitive member, and method for producing electrophotographic photosensitive member KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-05-08 US disclosed
US-9933712-B2 Multi-layer electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-04-03 US disclosed
US-9933712-B2 Multi-layer electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2018-04-03 US disclosed
US-9791793-B2 Electrophotographic photosensitive member KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2017-10-17 US disclosed
US-7745081-B2 Diphenyl amine derivative, production method therefor and electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2010-06-29 US disclosed
US-7745081-B2 Diphenyl amine derivative, production method therefor and electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2010-06-29 US disclosed
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-06-24 US disclosed
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-06-24 US disclosed
US-20070275314-A1 Diphenyl amine derivative, production method therefor and electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2007-11-29 US disclosed
US-20070275314-A1 Diphenyl amine derivative, production method therefor and electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2007-11-29 US disclosed
EP-1860095-A2 Diphenylamine derivative, production method therefor and electrophotographic photoconductor Kyocera Mita Corporation (JP) 2007-11-28 EP disclosed
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2007-06-21 US disclosed
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2007-06-21 US disclosed
US-4153719-A Aromatic diketones STERLING DRUG INC. (US) 1979-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160687-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 MAOA 1500/4885MAOB 739/4885NFE2L2 253/4885
US-20070142671-A1 ORGANIC ELECTROLUMESCENCE DEVICE SCO2, CHRM1, CHRM4 MAOA 1500/4885MAOB 739/4885NFE2L2 253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.