(E)-1,2-Di-P-Tolylethene

(E)-1,2-Di-P-Tolylethene

SCHEMBL1793692

Cc1ccc(/C=C\c2ccc(C)cc2)cc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 6/20 0.74
RELA Q04206 1/20 0.67
PTGS1 P23219 2/20 0.61
PTGS2 P35354 2/20 0.61
ALOX5 P09917 1/20 0.61
CA1 P00915 1/20 0.59
CYP2A6 P11509 1/20 0.58
ACHE P22303 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
FBP1 P09467 1/20 0.54
TUBB4A P04350 1/20 0.54
TUBB P07437 1/20 0.54
TUBA3C P0DPH7 1/20 0.54
TUBA1B P68363 1/20 0.54
TUBA4A P68366 1/20 0.54
TUBB4B P68371 1/20 0.54
TUBB3 Q13509 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(E)-1,2-Di-P-Tolylethene SCHEMBL1305582 1.00 NFE2L2 (0.74) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL318785 1.00 NFE2L2 (0.74) NFE2L2RELAPTGS1PTGS2ALOX5
(E)-1,2-Di-P-Tolylethene SCHEMBL1305580 1.00 NFE2L2 (0.74) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL318786 1.00 NFE2L2 (0.74) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL700269 0.88 NFE2L2 (0.61) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL4585865 0.88 NFE2L2 (0.61) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL7164327 0.88 NFE2L2 (0.61) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL4585859 0.88 NFE2L2 (0.61) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL4585867 0.88 NFE2L2 (0.61) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL1239547 0.88 NFE2L2 (0.61) NFE2L2RELAPTGS1PTGS2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460994-B1 Method and apparatus to make evident one or more shocks received by a substrate HUTCHINSON SA (FR) 1995-03-15 EP claimed
US-5242830-A Detection of impact with fluorescent indicators by embedding microcapsules and releasing HUTCHINSON (FR) 1993-09-07 US claimed
EP-0460994-A1 Method and apparatus to make evident one or more shocks received by a substrate HUTCHINSON S.A. une SociÀ©té Anonyme dotée d'un Conseil de Surveillance et d'un Directoire (FR) 1991-12-11 EP claimed
CN-113024340-B Method for reducing alkyne into olefin by using nickel catalytic water as hydrogen source 长春工业大学 2023-10-20 CN disclosed
US-20200354487-A1 Method for Producing Polymer LG CHEM, LTD. (KR) 2020-11-12 US disclosed
WO-2020198464-A1 HIGHLY SELECTIVE ELECTROCHEMICAL HYDROGENATION OF ALKYNES THE TRUSTEES OF INDIANA UNIVERSITY (US) 2020-10-01 WO disclosed
EP-3640267-A1 PREPARATION METHOD FOR POLYMER LG Chem, Ltd. (KR) 2020-04-22 EP disclosed
EP-1637551-B1 PROCESS FOR PRODUCING POLYMER NIPPON SODA CO (JP) 2013-02-27 EP disclosed
US-7951887-B2 Process for producing a polymer NIPPON SODA CO., LTD. (JP) 2011-05-31 US disclosed
US-20070015890-A1 Process for producing polymer NIPPON SODA CO., LTD. (JP) 2007-01-18 US disclosed
EP-1637551-A1 PROCESS FOR PRODUCING POLYMER NIPPON SODA CO., LTD. (JP) 2006-03-22 EP disclosed
EP-0460994-B1 Method and apparatus to make evident one or more shocks received by a substrate HUTCHINSON SA (FR) 1995-03-15 EP disclosed
US-5242830-A Detection of impact with fluorescent indicators by embedding microcapsules and releasing HUTCHINSON (FR) 1993-09-07 US disclosed
EP-0460994-A1 Method and apparatus to make evident one or more shocks received by a substrate HUTCHINSON S.A. une SociÀ©té Anonyme dotée d'un Conseil de Surveillance et d'un Directoire (FR) 1991-12-11 EP disclosed