SCHEMBL9972122

SCHEMBL9972122

Cc1ccccc1C=CC=Cc1ccc(N(C=C(c2ccccc2)c2ccccc2)c2ccc(C=CC=Cc3ccccc3C)cc2C)cc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.32
RAB9A P51151 2/20 0.32
KDM4E B2RXH2 1/20 0.32
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
TTR P02766 1/20 0.31
ALOX5 P09917 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
LMNA P02545 2/20 0.31
MAPT P10636 2/20 0.31
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
APP P05067 1/20 0.31
HTT P42858 1/20 0.30
RELA Q04206 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9972123 0.87 ALDH1A1 (0.33) RAB9AKDM4ETTRALOX5PTGS1
SCHEMBL9972117 0.87 TTR (0.43) RAB9ATTRALOX5PTGS1PTGS2
SCHEMBL9972132 0.84 TTR (0.43) RAB9ATTRALOX5PTGS1PTGS2
SCHEMBL9972118 0.83 SNCA (0.34) SNCARAB9AKDM4ETTRALOX5
SCHEMBL9972127 0.81 TTR (0.33) RAB9AKDM4ETTRALOX5PTGS1
SCHEMBL13242000 0.81 ALDH1A1 (0.38) SNCATTRALOX5PTGS1PTGS2
SCHEMBL9972120 0.79 PTGS2 (0.41) RAB9AKDM4EPTGS2LMNAMAPT
SCHEMBL13840797 0.78 TRPA1 (0.38) SNCARAB9AKDM4EALOX5PTGS1
SCHEMBL9973916 0.78 CYP2A6 (0.36) RAB9APTGS2LMNAMAPTNPC1
SCHEMBL9972133 0.78 TTR (0.35) RAB9AKDM4ETTRALOX5PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120156599-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME SHARP KABUSHIKI KAISHA (JP) 2012-06-21 US disclosed
US-20120156599-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS INCLUDING THE SAME SHARP KABUSHIKI KAISHA (JP) 2012-06-21 US disclosed