Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9972817 | 0.86 | — | — | |
| SCHEMBL9972820 | 0.85 | PLA2G4B (0.38) | — | |
| SCHEMBL13148759 | 0.80 | BHMT (0.32) | BHMT | |
| SCHEMBL5703321 | 0.73 | HDAC1 (0.50) | — | |
| SCHEMBL215964 | 0.72 | FFAR3 (0.35) | BHMT | |
| SCHEMBL957226 | 0.72 | FFAR3 (0.35) | BHMT | |
| SCHEMBL12764376 | 0.72 | PLA2G4B (0.35) | — | |
| SCHEMBL27513618 | 0.71 | LMNA (0.52) | BHMT | |
| SCHEMBL13148757 | 0.71 | — | — | |
| SCHEMBL30151138 | 0.70 | CA2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120157659-A1 | AFFINITY PEPTIDES AND METHOD FOR PURIFICATION OF RECOMBINANT PROTEINS | SIGMA-ALDRICH CO. (US) | 2012-06-21 | — | — | US | disclosed |
| US-7897376-B2 | Lysis reagents comprising at least two trialkylammonioalkylsulfonates, and a capture ligand specific for the target coating the interior surface of a multiwell plate; one step extraction not requiring centrifugation of the cellular solution | SIGMA-ALDRICH CO. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7799561-B2 | Affinity peptides and method for purification of recombinant proteins | SIGMA-ALDRICH, CO. (US) | 2010-09-21 | — | — | US | disclosed |
| US-7741053-B2 | Processes for purification of recombinant proteins | SIGMA-ALDRICH CO. (US) | 2010-06-22 | — | — | US | disclosed |
| US-7709612-B2 | Metal chelating compositions for protein purification, detection or binding | SIGMA-ALDRICH CO. (US) | 2010-05-04 | — | — | US | disclosed |
| US-20080064093-A1 | COMPOSITIONS AND METHODS EMPLOYING ZWITTERIONIC DETERGENT COMBINATIONS | SIGMA ALDRICH COMPANY (US) | 2008-03-13 | — | — | US | disclosed |
| US-7282475-B2 | Compositions and methods employing zwitterionic detergent combinations | SIGMA-ALDRICH CO. (US) | 2007-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157659-A1 | AFFINITY PEPTIDES AND METHOD FOR PURIFICATION OF RECOMBINANT PROTEINS | RPS27A, AEBP2, MRPL21 | BHMT 3526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.