SCHEMBL997411

SCHEMBL997411

CC(N(C)C)N1CCNCC1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
OPRD1 P41143 1/20 0.33
CYP2D6 P10635 1/20 0.32
CYP19A1 P11511 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM5 P08912 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10522315 1.00 MEN1 (0.34) MEN1KMT2AOPRD1CYP2D6CYP19A1
SCHEMBL4934569 0.91 OPRM1 (0.33) MEN1KMT2AOPRD1SLC6A2SLC6A4
Piperazine SCHEMBL28274258 0.82 MC4R (0.33) CYP2D6CHRM2CHRM1CHRM5CHRM3
SCHEMBL6367938 0.81
SCHEMBL28273095 0.78 CHRM2 (0.34) MEN1KMT2ACYP2D6CYP19A1CHRM2
SCHEMBL27447207 0.78 CHRM5 (0.31) MEN1KMT2ACHRM5CHRM3
SCHEMBL7717735 0.75 OPRD1 (0.33) MEN1KMT2AOPRD1CHRM5CHRM3
SCHEMBL1627655 0.75 OPRD1 (0.36) MEN1KMT2AOPRD1SLC6A2SLC6A4
SCHEMBL28379465 0.75 CHRM2 (0.33) MEN1KMT2AOPRD1CHRM2CHRM1
SCHEMBL109412 0.74 FDPS (0.32) CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108779353-A Curable polyester polyols and their use in thermosetting soft-feel coating formulations 伊士曼化工公司 2018-11-09 CN claimed
EP-2890559-A1 MODIFIED ETHYLENE-BASED FILMS TO PROMOTE ISOCYANATE CHEMICAL REACTIONS IN POLYURETHANE LAMINATING ADHESIVES Dow Global Technologies LLC (US) 2015-07-08 EP claimed
US-20150183193-A1 Modified Ethylene-Based Films to Promote Isocyanate Chemical Reactions in Polyurethane Laminting Adhesives DOW GLOBAL TECHNOLOGIES LLC (US) 2015-07-02 US claimed
CN-104755261-A Modified vinyl film for promoting chemical reaction of isocyanate in polyurethane laminating adhesive DOW GLOBAL TECHNOLOGIES INC 2015-07-01 CN claimed
CN-103333156-B Preparation method of 2-substituted arylethenyl-N-methylated quinoline derivative and application of 2-substituted arylethenyl-N-methylated quinoline derivative in preparation of drug for treating Alzheimer disease UNIV SUN YAT SEN 2015-03-11 CN claimed
WO-2014100921-A1 FOAM GASKET AND BONDING TAPE BASED ON POLYURETHANE DISPERSIONS SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2014-07-03 WO claimed
WO-2014036099-A1 MODIFIED ETHYLENE-BASED FILMS TO PROMOTE ISOCYANATE CHEMICAL REACTIONS IN POLYURETHANE LAMINATING ADHESIVES DOW GLOBAL TECHNOLOGIES LLC (US) 2014-03-06 WO claimed
CN-103333156-A Preparation method of 2-substituted arylethenyl-N-methylated quinoline derivative and application of 2-substituted arylethenyl-N-methylated quinoline derivative in preparation of drug for treating Alzheimer disease UNIV ZHONGSHAN 2013-10-02 CN claimed
JP-2000510188-A 2000-08-08 JP claimed
EP-0898587-A1 MECHANICALLY FROTHED POLYURETHANE FOAM PREPARED FROM A POLYURETHANE FORMULATION INCLUDING AN ORGANO-METALLIC CATALYST AND A TERTIARY AMINE CATALYST THE DOW CHEMICAL COMPANY (US) 1999-03-03 EP claimed
WO-1997043326-A1 MECHANICALLY FROTHED POLYURETHANE FOAM PREPARED FROM A POLYURETHANE FORMULATION INCLUDING AN ORGANO-METALLIC CATALYST AND A TERTIARY AMINE CATALYST THE DOW CHEMICAL COMPANY (US) 1997-11-20 WO claimed
EP-0248146-B1 REACTION PRODUCTS AND THEIR USE AS CATALYSTS FOR THE PRODUCTION OF PLASTICS ON THE BASIS OF ISOCYANAT BAYER AG (DE) 1989-06-21 EP claimed
US-4818748-A HYPOTENSIVE AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1989-04-04 US claimed
EP-0150440-B1 ENAMEL MIXTURES BASED ON HYDANTOIN GROUP CONTAINING POLYMERS AND THEIR APPLICATION BAYER AG (DE) 1988-05-18 EP claimed
EP-0236874-A2 Renin inhibitors, their production and use, as well as derivatives of amino acids and amino aldehydes BAYER AG (DE) 1987-09-16 EP claimed
US-4433128-A REACTING AROMATIC POLYISOCYANATE WITH CASTOR OIL AND TRIMETHYLOLPR AKZO NV (NL) 1984-02-21 US claimed
JP-58162624-A None JP disclosed
EP-4380572-B1 FORMULATION FOR SUBSTITUTED 2-AMINOTHIAZOLES IN THE TREATMENT OF FUNGAL AND FUNGAL-BACTERIAL INFECTIONS OF THE NAIL ONYCHOPHARM GMBH (DE) 2025-10-01 EP disclosed
US-4147690-A MAGNESIUM HYDROXIDE, ALUMINA TRIHYDRATE THE BURNS & RUSSELL COMPANY OF BALTIMORE (US) 1979-04-03 US disclosed
US-4041019-A 1-(N-SUBSTITUTED CARBAMOYL)-IMIDAZOLES THE DOW CHEMICAL COMPANY (US) 1977-08-09 US disclosed