Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14244471 | 0.87 | GPR119 (0.65) | GPR119 | |
| SCHEMBL14244470 | 0.87 | GPR119 (0.65) | GPR119 | |
| SCHEMBL9974208 | 0.82 | GPR119 (0.43) | GPR119FAAH | |
| SCHEMBL17715353 | 0.82 | GPR119 (0.49) | GPR119 | |
| SCHEMBL15540981 | 0.80 | GPR119 (0.66) | GPR119 | |
| SCHEMBL15541138 | 0.80 | GPR119 (0.66) | GPR119 | |
| SCHEMBL15541559 | 0.80 | GPR119 (0.66) | GPR119 | |
| SCHEMBL15540977 | 0.80 | GPR119 (0.66) | GPR119 | |
| SCHEMBL15541558 | 0.80 | GPR119 (0.66) | GPR119 | |
| SCHEMBL15540979 | 0.80 | GPR119 (0.66) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012080476-A1 | FUSED DIHYDROPYRANS AS GPR119 MODULATORS FOR THE TREATMENT OF DIABETES, OBESITY AND RELATED DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-21 | — | — | WO | disclosed |