SCHEMBL9974607

SCHEMBL9974607

c1ccc(-c2cc(-c3ccccc3)c3ccc4c(ccc5c(-c6ccccc6)cc(-c6ccccc6)nc54)c3n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 1/20 0.49
ACACA Q13085 1/20 0.47
MEN1 O00255 5/20 0.47
KMT2A Q03164 5/20 0.47
ALDH1A1 P00352 4/20 0.47
ADORA2A P29274 4/20 0.47
ADORA1 P30542 4/20 0.47
HPGD P15428 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MAPT P10636 5/20 0.46
KDM4E B2RXH2 3/20 0.46
MAPK1 P28482 3/20 0.46
LMNA P02545 1/20 0.46
RECQL P46063 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MPI P34949 1/20 0.46
SQOR Q9Y6N5 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ACHE P22303 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23942 0.94 TOP1 (0.50) TOP1ACACAMEN1KMT2AALDH1A1
SCHEMBL12112655 0.92 ACACA (0.51) TOP1ACACAMEN1KMT2AALDH1A1
SCHEMBL27752791 0.92 TOP1 (0.49) TOP1ACACAMEN1KMT2AALDH1A1
SCHEMBL1745982 0.90 ACACA (0.50) TOP1ACACAMEN1KMT2AALDH1A1
SCHEMBL17899330 0.90 ACACA (0.50) TOP1ACACAMEN1KMT2AALDH1A1
SCHEMBL3358457 0.90 ACACA (0.50) TOP1ACACAMEN1KMT2AALDH1A1
SCHEMBL3358750 0.90 ACACA (0.50) TOP1ACACAMEN1KMT2AALDH1A1
SCHEMBL3698074 0.90 ACACA (0.50) TOP1ACACAMEN1KMT2AALDH1A1
SCHEMBL12648641 0.89 MAPT (0.50) TOP1ACACAMEN1KMT2AALDH1A1
SCHEMBL25850698 0.88 TOP1 (0.46) TOP1ACACAMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3333168-B1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2022-01-26 EP disclosed
US-10693083-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-06-23 US disclosed
US-20180166635-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-14 US disclosed
US-20180166635-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-14 US disclosed
US-20160285008-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE Konica Minolta, Inc. (JP) 2016-09-29 US disclosed
US-20160285008-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE Konica Minolta, Inc. (JP) 2016-09-29 US disclosed
EP-2651942-B1 ELECTROACTIVE 1,7- AND 4,10-DIAZACHRYSENE DERIVATIVES AND DEVICES MADE WITH SUCH MATERIALS DU PONT (US) 2016-03-16 EP disclosed
US-9269909-B2 Electroactive material and devices made with such materials E I DU PONT DE NEMOURS AND COMPANY (US) 2016-02-23 US disclosed
US-9269909-B2 Electroactive material and devices made with such materials E I DU PONT DE NEMOURS AND COMPANY (US) 2016-02-23 US disclosed
US-20130240866-A1 ELECTROACTIVE MATERIAL AND DEVICES MADE WITH SUCH MATERIALS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-09-19 US disclosed
US-20130240866-A1 ELECTROACTIVE MATERIAL AND DEVICES MADE WITH SUCH MATERIALS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-09-19 US disclosed
WO-2012082593-A2 ELECTROACTIVE MATERIAL AND DEVICES MADE WITH SUCH MATERIALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180166635-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 TOP1 594/4885ACACA 369/4885MEN1 394/4885
US-20160285008-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE EML4, L1CAM, OCIAD2 TOP1 4662/4885ACACA 4589/4885MEN1 3335/4885
US-10693083-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 TOP1 594/4885ACACA 369/4885MEN1 394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.